STAFF
Dr. Antonio Vicente Ferrer Montiel
Professor of Biochemistry and Molecular Biology, Universidad Miguel Hernandez
Unit
Molecular and Cellular Design
Subunit
Molecular Recognizement and Protein Engineering
Group
Sensory Neurobiology
aferrer@umh.es
+ 34 966 65 87 27
RESEARCH FIELDS
- Sensory neurobiology with a focus on molecular and cellular mechanisms of pain transduction
- Discovery and development of anti-nociceptive drugs.
- Structure-function studies on thermo-sensory ion channels.
PROFESSIONAL BACKGROUND
- Previous positions:
1. Fellowship from the Ministry of Health, Universidad de Alicante, Spain, 1986-1989.
2. Postdoctoral fellowship from the Ministry of Education, University of California San Diego, 1990-1992.
3.-Postdoctoral fellowship from NATO, University of California San Diego, 1993.
4. Postgraduate Researcher, University of California San Diego, 1994-1996.
5.-Assistant Project Scientist Step II; Dept. Biology, UCSD, USA. 1996.
6.-Assistant Project Scientist Step III. Dept. Biology, UCSD, USA. 1997.
7.-Assistant Professor of Biochemistry and Molecular Biology (Tenure-Track). University Miguel Hernández (UMH), Spain. 1999.
8.-Associate Professor (Tenure), UMH, Spain. 1999-2007.
9.-Full Professor, UMH, Spain. 2007-present.
10.-Director, Institute of Molecular and Cellular Biology, 2012-present.
- Postdoctoral positions:
1. Department of Physics, University of California San Diego, 1990-1993.
2. Department of Biology, Universitsy of California San Diego, 1993-1997. - PhD programme:
1.-Molecular Neurosciences, Institute of Neurosciences, Universidad de Alicante,1989 (Director: Prof. José A. Ferragut)
2.-Awarded the Prize to the Best Thesis, Universidad de Alicante, 1990. - Degree in Chemistry.
REPRESENTATIVE PUBLICATIONS
Devesa, I., et al. (2014)
Proceedings of the National Academy of Sciences of the United States of America, DOI: 10.1073/pnas.1420252111
Alpha-CGRP is essential for pro-algesic sensitization of TRPV1 in peptidergic C-type nociceptors.
Taberner, F., et al. (2014)
The Journal of Biological Chemistry, DOI: 10.1074/jbc.M114.577478
The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation
Bonache, M.A., et al. (2014)
ACS Combinatorial Science, DOI: 10.1021/co500005x
De novo design, synthesis, structure and validation of a library of helical peptides for modulation of protein-protein interactions.
Gregorio-Teruel, L., et al. (2014)
The Journal of General Physiology, DOI:10.1085/jgp.201311070
Mutation of I696 and W697 in the trp box of vanilloid receptor subtype modulate allosteric channel activation
Devesa I. and Ferrer-Montiel A. (2014)
The European Journal of Neuroscience, DOI: 10.1111/ejn.12455
Neurotrophins, endocannabinoids and thermoTRPs: a threesome in pain signalings.
PATENTS AND AVAILABLE TECHNOLOGIES
Neuronal exocytosis inhibiting peptide and cosmetic composition and pharmaceutical composition containing the peptide
Inventores: Blanes C, Llobregat M, Gil A, Fernández-Ballester G, Planells Cases R, Viniegra S, Gutierrez LM, Carbonell T, Pérez-Payá E, Ferrer-Montiel. A.
Nº : ES2160482 B1 (granted on 18/04/2002); EP1180524 B1 (granted on 30/08/2006); CA2370289 A1; US7015192 B1 (granted on 21/03/2006); US77473679 B1 (granted on 21/03/2006).
N-alkylglycine trimeres capable of blocking the response to chemical substances, thermal stimuli or mediators of neuronal receptor inflammation and compositions containing said trimeres
Inventores: Antonio Ferrer Montiel, Asia Fernández Carvajal, Carolina García Martínez, Carlos Belmonte Martínez, Wim van den Nest, Cristina Carreño Serraima.
Nº: ES2169691 B1 (granted on 16/03/2004); WO02/30956; EP1338605 A1; US2004/33958; AU9388201; BR200114802 A; CA2425520 A1; JP2004/511491; MX PA/a/03003158.
N-alkylglycine trimeres capable of protecting neurons against excitotoxic aggressions and compositions containing such trimeres
Inventores: Felipo V, Montoliu C, Planells Cases R, Merino J, Pérez-Payá E, Sánchez-Baeza F, Humet M, Messeguer A, Ferrer-Montiel, A.
Nº : ES2169690 B1 (granted on 16/03/2004); ES2267816 T3 (granted on 16/03/2007); WO02/28885; EP1338604 B1 (granted on 12/07/2006); US6992064 B1 (granted on 31/01/2006); AU2001291906 A; BRPI0114660 A; CA2427072 A1; JP2002-532467; KR 849739 (granted on 01/08/2008); MX244057 B (granted on 09/03/2007).
Compounds which can block the responses to chemical substances or thermal stimuli or mediators of inflammation of nociceptors, production method thereof and compositions containing same
Inventores: Fernández-Carvajal A, García-Martínez C, Belmonte C, Van Den Nest W, Carreño C., Ferrer-Montiel A.
Nº: ES2195787 B1 (granted on 01/06/2005); WO03/097670; EP1506970 A1; US7183430 B2 (granted on 27/02/2003); AU2003/231331; CA2486342 A1; JP2006/502975 ; MX PA/a/04011502.
Dermopharmaceutical or cosmetic composition comprising enkephaline-derived peptides for reducing and/or eliminating facial wrinkles
Inventores: Ferrer-Montiel A, Cebrián J, Puig A.
Nº: ES2259928 B1 (granted on 06/09/2007); WO2006/106164; EP1892247 A1; US11/910719; AU2006231273; BR 0609745-6; CA2608165 A1; JP2008-504786; MX PA/a/2007012504.
COMPANY AGREEMENTS
- BCN Peptides
- DiverDrugs