STAFF
Dr. Francisco Javier Gómez Pérez
Professor of Physical chemistry, Universidad Miguel Hernandez
Unit
Molecular and Cellular Design
Subunit
Molecular Recognizement and Protein Engineering
Group
Biothermodynamics of molecular recognition processes
jgomez@umh.es
+ 34 966 65 84 67
RESEARCH FIELDS
- Structural thermodynamical description of molecular recognition processes
- Therdynamics of protein folding.
- Development of strategies to prevent protein aggregation.
PROFESSIONAL BACKGROUND
- Previous positions:
1. Predoctoral fellowship from Universidad Nacional de Educación a Distancia (U.N.E.D.). Department of Chemistry. 1989-1992.
2. Postdoctoral Fellow. The Biocalorimetry Center. Departmet of Biology. The Johns Hopkins University. 1993–1995.
3. Research Associate Scientist. The Biocalorimetry Center. Departmet of Biology. The Johns Hopkins University. 1995–1997 - Postdoctoral positions: The Biocalorimetry Center. Departmet of Biology. The Johns Hopkins University. Structural thermodynamical description of molecular recognition processes (Prof. Ernesto Freire).
- PhD programme: PhD degree with Honors and Prize to the best Thesis at the Chemistry program, Universidad Nacional de Educación a Distancia (U.N.E.D.) – Consejo Superior de Investigaciones Científicas (C.S.I.C.). Directors: Profs. José Laynez Vallejo and Rosa Mª Claramunt Vallespí, 1992.
- Degree in Chemistry
REPRESENTATIVE PUBLICATIONS
Romero-Bevier M., et al. (2010)
PEDS: Protein Engineering, Design and Selection, DOI: 10.1093/protein/gzq045
The N-terminal domain of the enzyme I is a monomeric well-folded protein with a low conformational stability and residual structure in the unfolded state
Neira J.L. E. and Gómez J. (2004)
European Journal of Biochemistry, PMID: 10569937
Thermodynamic analysis of the conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein: characterization of cold denaturation and urea-protein.
Todd M.J. and J. Gómez J., et al. (2001)
Analytical Biochemistry, DOI: 10.1006/abio.2001.5218
Enzyme kinetics determined using calorimetry: A General Assay for Enzymatic Activity?
Gómez J. and Freire E. (1995)
Journal of Molecular Biology, DOI: 10.1017/S0954422414000031
Thermodynamic Mapping of the Inhibitor Binding Site of the Aspartic Protease Endothiapepsin.
Gómez J., et al. (1995)
Proteins: Structure, Function and Genetics, DOI: 10.1002/prot.340220410
The Heat Capacity of Proteins.