STAFF

Dr. Laura Marroquí Esclapez

Professor, Universidad Miguel Hernandez

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Unit
Molecular Diagnostic, Prognostic and Therapy

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Subunit
Diabetes and Metabolic disorders

Group
Diabetes Research Unit

+34 965222062

Website
Islet Biology Lab

@isletbiologylab

RESEARCH FIELDS 

  • We are a research team based at the Universidad Miguel Hernández de Elche, interested in pancreatic islet function and survival in health and diabetes. Our research aims to understand the molecular differences between alpha and beta cells that allow the former to survive during diabetes development. This knowledge might help us to protect beta cells and, therefore, to either prevent or slow diabetes progression in susceptible individuals

PROFESSIONAL BACKGROUND

  • Previous positions: 

1. Assistant Professor, Department of Physiology, Miguel Hernández University of Elche, Spain, 2019-.

  • Postdoctoral position:

1. Postdoctoral Juan de la Cierva-incorporación (IJCI-2015-24482). Institute of Bioengineering, Miguel Hernández University of Elche, Alicante, Spain, 2017-2019.

2. ULB Center for Diabetes Research, Medical Faculty, Université libre de Bruxelles, Brussels, Belgium, 2012-2017.

  • PhD in Bioengineering, IBMC Program, Institute of Bioengineering, Miguel Hernández University of Elche, Spain, 2012. (Director: Prof. Ivan Quesada).

Awarded the Prize to the Best Thesis, Miguel Hernández University of Elche, 2013.

  • Degree in Biochemistry, Miguel Hernández University of Elche, Spain, 2006.

 MARROQUÍ, L.

REPRESENTATIVE PUBLICATIONS

Martinez-Pinna J., et al. (2019)

Journal Title, DOI: 10.1007/s00125-019-4925-y

Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells.

Marroqui L., et al. (2018)

Journal Title, DOI: 10.1530/JOE-18-0362

Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes.

marroqui l., et al. (2017)

Journal Title, DOI: 10.1007/s00125-016-4201-3

Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes.

marroqui l., et al. (2015)

Journal Title, DOI:10.2337/db15-0362

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells.

marroqui l., et al. (2015)

Journal Title, DOI: 10.1016/j.ebiom.2015.03.012

Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes.

marroqui l., et al. (2015)

Journal Title, DOI: 10.7554/eLife.06990

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells.