{"id":1838,"date":"2023-06-13T11:23:41","date_gmt":"2023-06-13T11:23:41","guid":{"rendered":"https:\/\/newidibe.zeus.umh.es\/?page_id=1838"},"modified":"2025-03-03T09:48:07","modified_gmt":"2025-03-03T09:48:07","slug":"research","status":"publish","type":"page","link":"https:\/\/idibe.umh.es\/en\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

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Our lines of research<\/span><\/h1>\n

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The different research groups are organized in two research programs: molecular biotechnology and preclinical biotechnology. These programs contain several lines with specific objectives in which several groups are involved, in this way we favor interaction and collaboration among IDiBE members, optimizing resources and improving the results obtained.<\/p>\n

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Molecular Biotechnology<\/strong><\/span><\/h1>\n

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Preclinical Biotechnology<\/strong><\/span><\/h1>\n

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Research<\/b><\/h1>\n

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Bioactive Molecules<\/strong><\/span><\/h1>\n

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Nanobiomaterials<\/strong><\/span><\/h1>\n

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Peripheral Neuropathies<\/strong><\/span><\/h1>\n

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Biosensing and biorecognition<\/strong><\/span><\/h1>\n

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Diabetes Research<\/strong><\/span><\/h1>\n

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Liver and GI Diseases<\/strong><\/span><\/h1>\n

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Antiviral Strategies<\/strong><\/span><\/h1>\n

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Hard to Treat Cancers<\/strong><\/span><\/h1>\n

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Termodin\u00e1mica<\/strong><\/span><\/h1>\n

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Institutional Statement on The Use of Research Animals<\/b><\/h1>\n

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The\u00a0<\/span>Research, Development, and Innovation in Healthcare Biotechnology in Elche\u00a0<\/strong>(<\/span>IDiBE<\/a><\/span>) has joined the\u00a0<\/span> Agreement on Openness on Animal Research<\/a><\/span>,<\/span> promoted from the Federation of Scientific Societies in Spain\u00a0<\/strong><\/span>(<\/span>COSCE<\/a><\/span>), with the colaboration of the European Association of Research Animals<\/strong><\/span>\u00a0(<\/span>EARA<\/a><\/span>), and launched on 20 September 2016.<\/span><\/p>\n

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Ethics, Biosafety and Animal Experimentation Committee<\/b><\/h1>\n

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At IDiBE we have an Ethics, Biosafety and Animal Experimentation Committee<\/strong> made up of research and technical personnel, with knowledge and solvency in these areas, whose objective is to advise and ensure compliance with ethical provisions regarding experimentation. Likewise, it is tasked with supervising the appropriate use of our Biosafety Laboratory Level 2<\/strong><\/a>. Its decisions and recommendations are made by consensus and are based on scientific and ethical reasons.<\/p>\n

The Committee is coordinated by Dr. Paloma Alonso-Magdalena and its members are Dr. Enrique Barraj\u00f3n Catal\u00e1n, Dr. Asia Fern\u00e1ndez Carvajal, Dr. M\u00aa del Mar Ortega-Villaiz\u00e1n Romo, Dr. Jos\u00e9 Manuel Gonz\u00e1lez Navajas and Dr. Lourdes Renart.<\/p>\n

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Members of<\/b><\/h1>\n

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IDiBE is part of the main biotech associations at the national, regional and provincial levels. Firstly, we are an entity affiliated with the Spanish Association of Biocompanies (AseBio)<\/strong>, which groups and represents the interests of companies, associations, foundations, universities and technological and research centers that have been developing activities in the field of biotechnology in Spain for more than 25 years. More information about AseBio in this link<\/a>.<\/p>\n

At the regional level, we are part of BioVal<\/strong>, which is the Association of Companies and Entities in the BIO sector founded in 2006 and which encompasses Biotechnology, Biomedicine and Bioeconomy, and which constitute the cluster of the Valencian Community. You can learn more about this partnership here<\/a>.<\/p>\n

At the provincial level, we are part of the Association of Biotechnology Companies of the Province of Alicante (AEBA)<\/strong>, whose objectives are the defense of the common interests of the biotechnology sector, the need to improve its competitiveness and the search for meeting points in the generation of potential synergies. You can consult the information about AEBA at this link<\/a>.<\/p>\n

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IDiBE-UMH\/HGUE-FISABIO<\/b><\/h1>\n

Joint Research Unit<\/b><\/h1>\n

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The Miguel Hern\u00e1ndez University of Elche and the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (<\/span>FISABIO<\/a>) have an agreement for the creation of a Joint Research Unit among the personnel assigned to the <\/span>Institute of Research, Development and Innovation in Health Biotechnology of Elche<\/strong> (IDiBE<\/a>) and the research staff of the <\/span>General University Hospital of Elche<\/strong> (HGUE<\/a>).<\/span><\/p>\n

The objective of this mixed unit is to carry out research, development and innovation activities in the fields of clinical medicine and health biotechnology. It focuses on research into new technologies in the treatment and diagnosis of cancer, pain, diabetes and infectious diseases, among others.<\/p>\n

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ISABIAL – IDiBE <\/b>Joint Research Unit <\/b>on Bioprinting, Organoids and Organs-on-chip for Functional Biomodelling<\/b><\/h1>\n

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The Institute for Health and Biomedical Research of Alicante (ISABIAL<\/a>)<\/strong> and the Institute for Research, Development and Innovation in Health Biotechnology of Elche (IDiBE<\/a>)<\/strong> of the Miguel Hern\u00e1ndez University (UMH) have formalised the creation of the Joint Research Unit on Bioprinting, Organoids and Organs-on-chip for Functional Biomodels. This strategic collaboration seeks to harness the potential of both institutions to lead advances in the design, development and application of organoids, which simulate the characteristics and functions of human organs in the laboratory.<\/p>\n

Among the objectives of the new unit are the design and development of experimental and preclinical models (organoids and organ-on-a-chip), which reduce the use of experimental animals, for the screening of new molecules with antineoplastic, antiviral, antibiotic and antifungal capacities, both from natural origin and from synthetic chemotherapeutics or designed by combining molecular modelling and virtual screening techniques. In addition, the new unit aims to work on the design and development of new biomaterials and biosensors useful for the diagnosis and treatment of cancer and other pathologies.<\/p>\n

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Funding<\/b><\/h1>\n

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Our lines of researchThe different research groups are organized in two research programs: molecular biotechnology and preclinical biotechnology. These programs contain several lines with specific objectives in which several groups are involved, in this way we favor interaction and collaboration among IDiBE members, optimizing resources and improving the results obtained. Molecular Biotechnology Preclinical BiotechnologyResearch Bioactive […]<\/p>\n","protected":false},"author":23459,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

[et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_enable_color=\"off\" custom_padding=\"||4px|||\"][et_pb_row admin_label=\"row\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" text_font=\"Verdana|700|||||||\" text_font_size=\"30px\" header_font=\"|600|||||||\" header_font_size=\"50px\" header_2_font=\"|700||on|||||\" header_2_text_color=\"#003041\" header_2_font_size=\"54px\" header_font_size_tablet=\"\" header_font_size_phone=\"35px\" header_font_size_last_edited=\"on|phone\"]<\/p>

Nuestras<\/b> l\u00edneas de investigaci\u00f3n<\/h1>

[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_font_size=\"20px\" text_line_height=\"1.6em\"]<\/p>

El programa de investigaci\u00f3n del IDiBE se organiza en dos l\u00edneas de investigaci\u00f3n principales: biotecnolog\u00eda molecular y biotecnolog\u00eda precl\u00ednica<\/span>\u00a0y cada una de ellas agrupa las actividades de m\u00faltiples equipos. Cada l\u00ednea de investigaci\u00f3n se estructura en sub-l\u00edneas con objetivos espec\u00edficos. El objetivo de esta estructura es aprovechar al m\u00e1ximo las capacidades de cada equipo<\/span> y favorecer la comunicaci\u00f3n fluida y las sinergias que surgen de la multidisciplinariedad. Queremos promover colaboraciones internas fruct\u00edferas<\/span> y un uso productivo de todos nuestros recursos.<\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\" column_structure=\"1_2,1_2\"][et_pb_column _builder_version=\"4.2.2\" type=\"1_2\"][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/molecula-bioactiva-scaled-1.jpeg\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/biotecnologia-molecular\/\" hover_enabled=\"0\" border_radii=\"on|14px|14px|14px|14px\" custom_css_after_last_edited=\"off|desktop\" custom_css_after__hover_enabled=\"on|desktop\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/molecula-bioactiva-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\" custom_padding=\"105px||||false|false\"]<\/p>

\u00a0<\/h1>

Biotecnolog\u00eda molecular<\/strong><\/span><\/h1>

[\/et_pb_text][\/et_pb_column][et_pb_column _builder_version=\"4.2.2\" type=\"1_2\"][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/inmunofarm-scaled-1.jpeg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/biotecnologia-preclinica\/\" hover_enabled=\"0\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/inmunofarm-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\" custom_padding=\"105px||||false|false\"]<\/p>

\u00a0<\/h1>

\u00a0<\/h1>

Biotecnolog\u00eda precl\u00ednica<\/strong><\/span><\/h1>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_margin=\"||-1px|||\" custom_padding=\"0px||70px||false|\" min_height__hover_enabled=\"off|desktop\"][et_pb_row column_structure=\"1_3,1_3,1_3\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"83px||0px|||\" disabled=\"on\"][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/molecula-bioactiva-scaled-1.jpeg\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/moleculas-bioactivas\/\" border_radii=\"on|14px|14px|14px|14px\" custom_css_after_last_edited=\"off|desktop\" custom_css_after__hover_enabled=\"on|desktop\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/molecula-bioactiva-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Mol\u00e9culas Bioactivas<\/strong><\/span><\/h1>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/nanomaterial-fluorescente-scaled-1.jpeg\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/nanomateriales-fluorescentes\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|desktop\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/nanomaterial-fluorescente-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Nanomateriales Fluorescentes<\/strong><\/span><\/h1>

\u00a0<\/p>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/investigacion-sensorial-scaled-1.jpeg\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/unidad-de-investigacion-sensorial\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/investigacion-sensorial-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Unidad de Investigaci\u00f3n Sensorial<\/strong><\/span><\/h1>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#000000\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/investigacion-diabetes-scaled-1.jpeg\" background_blend=\"difference\" width=\"100%\" min_height=\"282px\" custom_padding=\"|||0px||\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/investigacion-diabetes\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/investigacion-diabetes-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Investigaci\u00f3n Diabetes<\/span><\/strong><\/span><\/h1>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/inmunofarm-scaled-1.jpeg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/inmunofarmacologia-e-inmuno-oncologia\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/inmunofarm-fondo-scaled-1.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

\u00a0<\/h1>

\u00a0 Inmunofarmacolog\u00eda e Inmuno-oncolog\u00eda<\/strong><\/span><\/h1>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/canales-ionicos-scaled-1.jpg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/estructura-funcional-de-canales-ionicos\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/canales-ionicos-fondo-scaled-1.jpg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Estructura Funcional de Canales I\u00f3nicos<\/strong><\/span><\/h1>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/estrategia-antiviral-scaled-e1646396459957.jpeg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/estrategias-antivirales\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/estrategia-antiviral-fondo-scaled-e1646396510830.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Estrategias Antivirales<\/strong><\/span><\/h1>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/oncologia-scaled-e1646396294116.jpeg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/oncologia-molecular\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/oncologia-fondo-scaled-e1646396241258.jpeg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

\u00a0<\/h1>

Oncolog\u00eda Molecular<\/strong><\/span><\/h1>

[\/et_pb_text][et_pb_text module_class=\"image\" _builder_version=\"4.2.2\" text_font=\"|700|||||||\" text_text_color=\"#ffffff\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/termodinamica-scaled-1.jpg\" background_blend=\"difference\" min_height=\"282px\" link_option_url=\"https:\/\/newidibe.zeus.umh.es\/termodinamica\/\" border_radii=\"on|14px|14px|14px|14px\" background__hover_enabled=\"on|hover\" background_image__hover=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/termodinamica-fondo-scaled-1.jpg\" background_enable_image__hover=\"on\"]<\/p>

\u00a0<\/h1>

Termodin\u00e1mica<\/strong><\/span><\/h1>

\u00a0<\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_enable_color=\"off\" custom_padding=\"||4px|||\"][et_pb_row admin_label=\"row\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" text_font=\"Verdana|700|||||||\" text_font_size=\"30px\" header_font=\"|600|||||||\" header_font_size=\"50px\" header_2_font=\"|700||on|||||\" header_2_text_color=\"#003041\" header_2_font_size=\"54px\" header_font_size_tablet=\"\" header_font_size_phone=\"35px\" header_font_size_last_edited=\"on|phone\"]<\/p>

Declaraci\u00f3n Institucional\u00a0<\/b><\/h1>

Sobre el Uso de Animales de Experimentaci\u00f3n<\/h1>

[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_font_size=\"20px\" text_line_height=\"1.6em\"]<\/p>

El\u00a0<\/span>Instituto de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n en Biotecnolog\u00eda Sanitaria de Elche<\/strong>\u00a0(<\/span>IDiBE<\/strong><\/a>) se ha adherido al\u00a0<\/span>Acuerdo de Transparencia en Experimentaci\u00f3n Animal<\/a>, promovido desde la\u00a0<\/span>Confederaci\u00f3n de Sociedades Cient\u00edficas de Espa\u00f1a<\/strong>\u00a0(<\/span>COSCE<\/strong><\/a>), con la colaboraci\u00f3n de la\u00a0<\/span>Asociaci\u00f3n Europea para la Investigaci\u00f3n Animal<\/strong>\u00a0(<\/span>EARA<\/strong><\/a>) y lanzado el 20 de septiembre de 2016.<\/span><\/p>

[\/et_pb_text][et_pb_button button_url=\"https:\/\/idibe.umh.es\/es\/investigacion\/declaracion-institucional-animales-experimentacion\/\" url_new_window=\"on\" button_text=\"LEER M\u00c1S\" button_alignment=\"center\" _builder_version=\"4.2.2\" custom_button=\"on\" button_text_size=\"24px\" button_text_color=\"#ffffff\" button_bg_color=\"#ab1a2d\" button_border_width=\"0px\" button_border_radius=\"30px\" button_font=\"|600|||||||\" custom_margin=\"20px||60px||false|false\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_enable_color=\"off\"][et_pb_row admin_label=\"row\" _builder_version=\"4.2.2\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" text_font=\"Verdana|700|||||||\" text_font_size=\"30px\" header_font=\"|600|||||||\" header_font_size=\"50px\" header_2_font=\"|700||on|||||\" header_2_text_color=\"#003041\" header_2_font_size=\"54px\" header_font_size_tablet=\"\" header_font_size_phone=\"28px\" header_font_size_last_edited=\"on|phone\"]<\/p>

\u00daltimas\u00a0<\/b>Publicaciones<\/h1>

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En IDiBE valoramos la calidad sobre la cantidad. Siempre nos esforzamos por hacer contribuciones significativas a la sociedad y la atenci\u00f3n m\u00e9dica y compartir nuestros resultados en revistas internacionalmente reconocidas, revisadas por expertos y de alto impacto.<\/span><\/p>

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[\/et_pb_text][et_pb_slider show_pagination=\"off\" _builder_version=\"4.2.2\" header_font=\"||||||||\" body_font=\"||||||||\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/publications.png\" custom_button=\"on\" button_bg_color=\"#ab1a2d\" button_border_width=\"0px\" button_border_radius=\"10px\" height_tablet=\"auto\" height_phone=\"auto\" height_last_edited=\"on|phone\" custom_margin=\"-34px|100px||100px|false|true\" custom_margin_tablet=\"|20px||20px|false|true\" custom_margin_phone=\"|10px||10px|false|true\" custom_margin_last_edited=\"on|phone\" auto=\"on\" border_width_all_image=\"20px\"][et_pb_slide heading=\"Nutrients\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]<\/p>

Cuy\u00e1s, E., et al., (2019)<\/p>

Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1\/KDM1A<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Plos One\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]<\/p>

Bell\u00f3-P\u00e9rez, M., et al., (2019)<\/p>

Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Nutrients\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]<\/p>

Olivares-Vicente, M. et al. (2019)<\/p>

The Potential Synergistic Modulation of AMPK by Lippia citriodora Compounds as a Target in Metabolic Disorders<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Biomolecules\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Ruiz-Torres, V. et al. (2019)<\/p>

Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Revista Clinica Espa\u00f1ola\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Zapater, P. (2018)<\/p>

Los estudios gen\u00e9ticos y la enfermedad hep\u00e1tica alcoh\u00f3lica
<\/span>Genetic studies and alcoholic liver disease<\/span><\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Vaccines\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Nombela, I, et al. (2019)<\/p>

Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Vaccines\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Puente-Mar\u00edn, S. et al. (2018)<\/p>

Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Front. Immunol.\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Puente-Mar\u00edn, S., et al. (2019)<\/p>

Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNF\u03b1 and a G-VHSV Fragment<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Biomolecular Structure and Dynamics\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Villala\u00edn, J. (2019)<\/p>

Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Front. Immunol.\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" custom_button=\"on\" button_bg_color=\"#c0172d\"]Chico, V., P. (2019)<\/p>

IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Cells\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" body_font=\"||||||||\"]Nombela, I. et al. (2019)<\/p>

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Biomolecular Structure and Dynamics\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" body_font=\"||||||||\"]Carpio, L. E. et al. (2019)<\/p>

Identification of the phospholipid binding regions of the envelope E protein of flaviviruses by molecular dynamics<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\" body_font=\"||||||||\"]Renart, M. L., et al. (2019)<\/p>

Conformational plasticity in the KcsA potassium channel pore helix revealed by homo-FRET studies<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Front. Immunol.\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Jung, M-H. et al. (2019)<\/p>

The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Biochimica et Biophysica Acta - Biomembranes\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Poveda, J. A., et al. (2019)<\/p>

Modulation of the potassium channel KcsA by anionic phospholipids: Role of arginines at the non-annular lipid binding sites<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Nutrients\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cuy\u00e0s, E., et al. (2019)<\/p>

Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1\/KDM1A<\/em><\/p>

VIEW PAPER<\/a>
[\/et_pb_slide][et_pb_slide heading=\"Food and Chemical Toxicology\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cuy\u00e0s, E., et al. (2019)<\/p>

The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"International Journal of Molecular Sciences\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Giudici, A. M. et al. (2019)<\/p>

Accessibility of Cations to the Selectivity Filter of KcsA in the Inactivated State: An Equilibrium Binding Study<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"ACS Chemical Neuroscience\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]P\u00e9rez de Vega, M. J., et al. (2019)<\/p>

1-(2\u2032,5\u2032-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of \u03b17 Nicotinic Receptors with Analgesic and Neuroprotective Activity<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Food and Chemical Toxicology\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cuy\u00e0s, E., et al. (2019)<\/p>

Revisiting silibinin as a novobiocin-like Hsp90\u202fC-terminal inhibitor: Computational modeling and experimental validation<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"The FASEB Journal\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Sol\u00e9, L., et al. (2019)<\/p>

The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"In Silico Approaches for TRP Channel Modulation. In TRP Channels\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Nikolaeva Koleva, M. & Fern\u00e1ndez-Ballester, G., et al. (2019)<\/p>

In Silico Approaches for TRP Channel Modulation<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Pharmaceutics\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Mart\u00ednez Ortega, L., et al. (2019)<\/p>

Development of A New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Molecular and Cellular Endocrinology\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Soriano, S. et al. (2019)<\/p>

Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"In Silico Approaches for TRP Channel Modulation. In TRP Channels\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cordero-S\u00e1nchez, C. et al. (2019)<\/p>

Fluorescence-Based Functional Assays for Ca2+-Permeable ThermoTRP Channels<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Medicinal Chemistry\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cordero-S\u00e1nchez, C. et al. (2019)<\/p>

A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Cordero-S\u00e1nchez, C. et al. (2019)<\/p>

Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"International Journal of Molecular Sciences \" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Arribas-Bl\u00e1zquez, M. et al. (2019)<\/p>

Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Neuroscience\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Cobo, R. et al. (2019)<\/p>

Mechanisms of Blockade of the Muscle-Type Nicotinic Receptor by Benzocaine, a Permanently Uncharged Local Anesthetic<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Diabetologia\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Martinez-Pinna, J. et al. (2019)<\/p>

Oestrogen receptor \u03b2 mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"The Journal of Membrane Biology\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Galiano, V. et al. (2020)<\/p>

Location, Orientation and Aggregation of Bardoxolone-ME, CDDO-ME, in a Complex Phospholipid Bilayer Membrane<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Aging\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]Verdura, S., et al. (2020)<\/p>

Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Bell\u00f3-P\u00e9rez, M. et al. (2020)<\/p>

Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Antioxidants\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

S\u00e1nchez-Marzo, N. et al. (2020)<\/p>

Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Aging\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Cuy\u00e1s, E. et al. (2020)<\/p>

The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Viruses\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Encinar, J. A. & Men\u00e9ndez, J. A. (2020)<\/p>

Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2\u2019-O-Methylation of Viral RNA<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Endocrinology\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Alonso-Magdalena, P. & Nadal, A. (2020)<\/p>

The Commonly Overlooked Factor. Commentary on: \"Environmental Obesogens and their Impact on Susceptibility to Obesity\"<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Environmental Health\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Muncke, J. et al. (2020)<\/p>

Impacts of food contact chemicals on human health: a consensus statement<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Viruses\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Agull\u00f3-Chazarra, L. et al. (2020)<\/p>

Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"International Journal of Molecular Sciences\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Renart, M. L. et al. (2020)<\/p>

Modulation of Function, Structure and Clustering of K+ Channels by Lipids: Lessons Learnt from KcsA<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"International Journal of Molecular Sciences\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Legler, J. et al. (2020)<\/p>

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Hepatology International\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Almenara, S. et al. (2020)<\/p>

Functionality of beta-adrenergic receptors in patients with cirrhosis treated chronically with non-selective beta-blockers<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Food and Chemical Toxicology\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Boronat-Belda, T. et al. (2020)<\/p>

Functionality of beta-adrenergic receptors in patients with cirrhosis treated chronically with non-selective beta-blockers<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"ACS Chemichal Neuroscience\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Journigan, V. B. et al. (2020)<\/p>

Structure-Based Design of Novel Biphenyl Amide Antagonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 8 Channels with Potential Implications in the Treatment of Sensory Neuropathies<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Agricultural and Food Chemistry\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Pozuelo-S\u00e1nchez, I. et al. (2020)<\/p>

Postprandial Lipemia Modulates Pancreatic Alpha-Cell Function in the Prediction of Type 2 Diabetes Development: The CORDIOPREV Study<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Medicinal Chemistry\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Bertamino, A. et al. (2020)<\/p>

Exploration of TRPM8 Binding Sites by \u03b2-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Metabolism\" _builder_version=\"3.23.3\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Quesada-Candela, C. et al. (2020)<\/p>

Morphological and functional adaptations of pancreatic alpha-cells during late pregnancy in the mouse<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Biomedicines\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

\u00c1lvarez-Mart\u00ednez, F. J. et al. (2020)<\/p>

Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Expert Opinion on Therapeutic Targets\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Fern\u00e1ndez-Ballester, G. et al. (2020)<\/p>

Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Bonache, M. A. et al. (2020)<\/p>

Highly functionalized \u03b2-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Expert Opinion on Investigational Drugs\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Fern\u00e1ndez-Carvajal, A. et al. (2020)<\/p>

Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"International Journal of Molecular Sciences \" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Dionisi, M. et al. (2020)<\/p>

Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

\u00c1varez-Mart\u00ednez, F. J. et al. (2021)<\/p>

The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Scientific Reports\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Nikolaeva-Koleva, M. et al. (2021)<\/p>

A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Chemosphere\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Marroqu\u00ed, L. et al. (2021)<\/p>

Bisphenol-S and Bisphenol-F alter mouse pancreatic \u03b2-cell ion channel expression and activity and insulin release through an estrogen receptor ER\u03b2 mediated pathway<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"British Journal of Pharmacology\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Villaba-Riquelme, E. et al. (2022)<\/p>

Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Antioxidants\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Salazar-Bermeo, J. et al. (2021)<\/p>

Potential of Persimmon Dietary Fiber Obtained from Byproducts as Antioxidant, Prebiotic and Modulating Agent of the Intestinal Epithelial Barrier Function<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Journal of Cosmetic Dermatology\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Mart\u00edn-Mart\u00ednez, A. et al. (2022)<\/p>

High global antioxidant protection and stimulation of the collagen synthesis of new anti-aging product containing an optimized active mix<\/em><\/p>

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[\/et_pb_slide][et_pb_slide heading=\"Pharmaceutics\" _builder_version=\"4.2.2\" header_level=\"h4\" header_font=\"Raleway||||||||\" header_font_size=\"29px\"]<\/p>

Gea-Botella, S. et al. (2021)<\/p>

Carotenoids from Persimmon (Diospyros kaki Thunb.) Byproducts Exert Photoprotective, Antioxidative and Microbial Anti-Adhesive Effects on HaCaT<\/em><\/p>

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[\/et_pb_slide][\/et_pb_slider][et_pb_button button_url=\"https:\/\/idibe.umh.es\/latest-publications\/\" url_new_window=\"on\" button_text=\"VER TODOS LOS PAPERS\" button_alignment=\"center\" _builder_version=\"4.2.2\" custom_button=\"on\" button_text_size=\"24px\" button_text_color=\"#ffffff\" button_bg_color=\"#ab1a2d\" button_border_width=\"0px\" button_border_radius=\"30px\" button_font=\"|600|||||||\" custom_margin=\"20px||60px||false|false\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" admin_label=\"section\" _builder_version=\"4.2.2\" background_image=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/vaccine-gbf1e84844_1920.jpg\" height=\"422px\" disabled=\"on\"][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_color=\"#f9f9f9\" custom_padding=\"0px||0px|||\" disabled=\"on\"][et_pb_row column_structure=\"3_5,2_5\" make_equal=\"on\" _builder_version=\"4.2.2\"][et_pb_column type=\"3_5\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"20px\" header_3_font=\"|700|||||||\" header_3_text_color=\"#ffffff\" header_4_font=\"|700|||||||\" header_4_text_color=\"#ffffff\" header_4_font_size=\"17px\"]<\/p>

1. DISE\u00d1O Y DESARROLLO DE MOL\u00c9CULAS BIOACTIVAS<\/b><\/span><\/h3>

[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"16px\"]<\/p>

El grupo D&DBM est\u00e1 compuesto por un equipo interdisciplinar de investigadores y profesorado de las Universidad Miguel Hern\u00e1ndez de Elche. Nuestro principal inter\u00e9s se centra en el uso de los compuestos de origen natural para el tratamiento de diferentes enfermedades, basado siempre en la evidencia cient\u00edfica y sostenido por la continua b\u00fasqueda de la excelencia, el impacto social, medioambiental y econ\u00f3mico y la obtenci\u00f3n de resultados de alta calidad.<\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_5\" _builder_version=\"4.2.2\" custom_css_main_element=\"margin: auto;\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/lab-g203000079_1920.jpg\" align=\"center\" _builder_version=\"4.2.2\" background_color=\"rgba(0,0,0,0)\" width=\"100%\" max_width=\"100%\" border_width_all=\"-1px\" border_color_all=\"rgba(0,0,0,0)\" border_style_all=\"none\"][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_button button_text=\"READ MORE\" button_alignment=\"center\" _builder_version=\"4.2.2\" custom_button=\"on\" button_text_size=\"26px\" button_text_color=\"#ffffff\" button_bg_color=\"#f05227\" button_border_width=\"0px\" button_border_radius=\"30px\" button_font=\"|700|||||||\" custom_margin=\"20px||60px||false|false\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_padding=\"0px||0px|||\" disabled=\"on\"][et_pb_row column_structure=\"2_5,3_5\" make_equal=\"on\" _builder_version=\"4.2.2\"][et_pb_column type=\"2_5\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/diabetes-g679cd6ab8_1920.jpg\" align=\"center\" _builder_version=\"4.2.2\" background_color=\"rgba(0,0,0,0)\" width=\"100%\" max_width=\"100%\" border_width_all=\"-1px\" border_color_all=\"rgba(0,0,0,0)\" border_style_all=\"none\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_5\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"20px\" header_3_font=\"|700|||||||\" header_3_text_color=\"#ffffff\" header_4_font=\"|700|||||||\" header_4_text_color=\"#ffffff\" header_4_font_size=\"17px\"]<\/p>

2. UNIDAD DE INVESTIGACI\u00d3N\u00a0 B\u00c1SICA EN DIABETES<\/b><\/span><\/h3>

[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"16px\"]<\/p>

La diabetes mellitus se caracteriza por una hiperglucemia causada por una deficiencia de insulina. Su prevalencia est\u00e1 aumentando y alcanza la cifra de 425 millones de personas en todo el mundo (www.idf.org). En Espa\u00f1a, m\u00e1s del 13% de la poblaci\u00f3n adulta es diab\u00e9tica y 3 de cada 10 personas tienen problemas con el metabolismo de la glucosa.\u00a0<\/span><\/span><\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_button button_text=\"READ MORE\" button_alignment=\"center\" _builder_version=\"4.2.2\" custom_button=\"on\" button_text_size=\"26px\" button_text_color=\"#ffffff\" button_bg_color=\"#f05227\" button_border_width=\"0px\" button_border_radius=\"30px\" button_font=\"|700|||||||\" custom_margin=\"20px||60px||false|false\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_color=\"#f9f9f9\" custom_padding=\"0px||0px|||\" disabled=\"on\"][et_pb_row column_structure=\"3_5,2_5\" make_equal=\"on\" _builder_version=\"4.2.2\"][et_pb_column type=\"3_5\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"20px\" header_3_font=\"|700|||||||\" header_3_text_color=\"#ffffff\" header_4_font=\"|700|||||||\" header_4_text_color=\"#ffffff\" header_4_font_size=\"17px\"]<\/p>

3. ESTRATEGIAS ANTIVIRALES<\/b><\/span><\/h3>

\u00a0<\/h3>

[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#ffffff\" text_font_size=\"16px\"]<\/p>

Las enfermedades causadas por virus y bacterias causan enorme preocupaci\u00f3n y despiertan un gran inter\u00e9s en el campo de la sanidad humana y animal.<\/span> Los llamados agentes antivirales son mol\u00e9culas capaces de detener el avance de una infecci\u00f3n. Lo pueden hacer de diversas formas: impidiendo la entrada del virus a la c\u00e9lula, inhibiendo la replicaci\u00f3n del \u00e1cido nucleico viral, o interfiriendo con el ensamblaje de la part\u00edcula viral. Adem\u00e1s, la acci\u00f3n antiviral puede realizarse mediante la potenciaci\u00f3n de las respuestas inmunitarias innata y adaptativa del hospedador. <\/span>\u00a0<\/span><\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_5\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/coronavirus-g290f1b4ec_1920.jpg\" align=\"center\" _builder_version=\"4.2.2\" background_color=\"rgba(0,0,0,0)\" width=\"100%\" max_width=\"100%\" border_width_all=\"-1px\" border_color_all=\"rgba(0,0,0,0)\" border_style_all=\"none\"][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_button button_text=\"READ MORE\" button_alignment=\"center\" _builder_version=\"4.2.2\" custom_button=\"on\" button_text_size=\"26px\" button_text_color=\"#ffffff\" button_bg_color=\"#f05227\" button_border_width=\"0px\" button_border_radius=\"30px\" button_font=\"|700|||||||\" custom_margin=\"20px||60px||false|false\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/1838"}],"collection":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/users\/23459"}],"replies":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/comments?post=1838"}],"version-history":[{"count":0,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/1838\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media?parent=1838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}