{"id":2044,"date":"2023-07-04T10:20:27","date_gmt":"2023-07-04T10:20:27","guid":{"rendered":"https:\/\/newidibe.zeus.umh.es\/?page_id=2044"},"modified":"2025-09-08T16:57:22","modified_gmt":"2025-09-08T16:57:22","slug":"design-and-validation-of-nanobiomaterials","status":"publish","type":"page","link":"https:\/\/idibe.umh.es\/en\/design-and-validation-of-nanobiomaterials\/","title":{"rendered":"Design and validation of Nanobiomaterials"},"content":{"rendered":"

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Design and VALIDATION OF NANOBIOMATERIALS<\/b><\/span><\/h1>\n

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Our research area is focus on the design, synthesis and characterization of nanostructures based on polymeric materials with potential biological applications. The main interest of the group is the development of new nanostructured materials that can be used in drug delivery applications.<\/span><\/p>\n

Website:<\/b> https:\/\/nanobiomat.umh.es\/<\/a><\/span><\/p>\n

LinkedIn profile:<\/b>\u00a0<\/span>https:\/\/www.linkedin.com\/company\/grupo-dvn-idibe<\/span><\/a>\u00a0<\/span><\/span><\/span><\/p>\n

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Principal investigator<\/strong><\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” _builder_version=”4.16″ custom_margin=”0px||||false|false” custom_padding=”31px||3px||false|false” locked=”off” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_team_member name=”Ricardo Mallavia” position=”Principal investigator” image_url=”https:\/\/idibe.umh.es\/files\/2023\/03\/Ricardo-Mallavia-240×300.png” _builder_version=”4.16″ header_text_align=”center” header_text_color=”#000000″ position_text_align=”center” position_text_color=”#000000″ link_option_url=”https:\/\/idibe.umh.es\/en\/dr-ricardo-mallavia\/” link_option_url_new_window=”on” global_colors_info=”{}”][\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.17.4″ text_text_color=”#000000″ text_font_size=”18px” text_orientation=”justified” custom_padding=”||||false|false” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Other group members:<\/strong><\/p>\n

Amalia Mira (postdoc).\u00a0ORCID:\u00a00000-0002-1909-5498<\/a><\/span><\/p>\n

Roc\u00edo D\u00edaz Puertas<\/span>\u00a0<\/span>(postdoc). ORCID: 0000-0002-3288-5697<\/a><\/p>\n

Pedro Valent\u00edn Bad\u00eda Hern\u00e1ndez (predoc). ORCID: 0009-0000-5449-3611<\/a><\/p>\n

Paula del Carmen S\u00e1nchez Garc\u00eda (predoc). ORCID:\u00a00009-0008-0259-0055<\/a><\/div>\n

 <\/p>\n

Collaborator: \u00a0Alberto Falc\u00f3 (CSIC). ORCID:<\/span>\u00a00000-0001-7726-6577<\/a><\/span><\/p>\n

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Design and VALIDATION OF NANOBIOMATERIALSOur research area is focus on the design, synthesis and characterization of nanostructures based on polymeric materials with potential biological applications. The main interest of the group is the development of new nanostructured materials that can be used in drug delivery applications. Website: https:\/\/nanobiomat.umh.es\/ LinkedIn profile:\u00a0https:\/\/www.linkedin.com\/company\/grupo-dvn-idibe\u00a0Principal investigatorOther group members: Amalia Mira […]<\/p>\n","protected":false},"author":23459,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

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Grupo de dise\u00f1o y\u00a0<\/b><\/span>Validaci\u00f3n de Nanobiomateriales<\/strong><\/h1>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"65px||5px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" text_text_color=\"#000000\" text_font_size=\"18px\" custom_padding=\"||||false|false\"]<\/p>

Nuestra \u00e1rea de investigaci\u00f3n gira en torno al dise\u00f1o, s\u00edntesis y caracterizaci\u00f3n de nanoestructuras basadas en materiales polim\u00e9ricos con potenciales aplicaciones biol\u00f3gicas. El grupo se enfoca en desarrollar nuevos materiales nanoestructurados que puedan emplearse en aplicaciones de administraci\u00f3n de f\u00e1rmacos.<\/span><\/p>

Link p\u00e1gina LinkedIn:<\/b>\u00a0<\/span>https:\/\/www.linkedin.com\/company\/grupo-dvn-idibe<\/span><\/a>\u00a0<\/span><\/span><\/span><\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"||70px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" header_2_font_size_tablet=\"\" header_2_font_size_phone=\"40px\" header_2_font_size_last_edited=\"on|phone\"]<\/p>

Personal<\/strong><\/span><\/h2>

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Juan Alberto Falc\u00f3 Garci\u00e1<\/strong><\/span><\/p>

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Ricardo Mallavia Mar\u00edn<\/strong><\/span><\/p>

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M\u00aa Jos\u00e9 Mart\u00ednez Tom\u00e9<\/strong><\/span><\/p>

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Carmen Reyes Mateo Mart\u00ednez<\/strong><\/span><\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"3px||70px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" header_2_font_size_tablet=\"\" header_2_font_size_phone=\"40px\" header_2_font_size_last_edited=\"on|phone\"]<\/p>

Investigadores postdoctorales<\/span><\/strong><\/span><\/h2>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_3,1_3,1_3\" use_custom_gutter=\"on\" _builder_version=\"4.2.2\" custom_margin=\"0px||||false|false\" custom_padding=\"31px||3px||false|false\"][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/Francisco-Alvarez.jpg\" url_new_window=\"on\" align=\"center\" force_fullwidth=\"on\" _builder_version=\"4.2.2\" module_alignment=\"center\" custom_margin=\"||14px|||\" custom_padding=\"|50px||50px|false|false\"][\/et_pb_image][et_pb_text _builder_version=\"4.2.2\" text_orientation=\"center\" link_option_url_new_window=\"on\"]<\/p>

Amalia Mira Carri\u00f3<\/strong><\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"1px||70px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" header_2_font_size_tablet=\"\" header_2_font_size_phone=\"40px\" header_2_font_size_last_edited=\"on|phone\"]<\/p>

Estudiantes de doctorado<\/span><\/strong><\/span><\/h2>

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Marta Rubio Camacho<\/strong><\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/noelia-sanchez.jpg\" url_new_window=\"on\" align=\"center\" force_fullwidth=\"on\" _builder_version=\"4.2.2\" module_alignment=\"center\" custom_margin=\"||14px|||\" custom_padding=\"|50px||50px|false|false\"][\/et_pb_image][et_pb_text _builder_version=\"4.2.2\" text_orientation=\"center\" link_option_url_new_window=\"on\"]<\/p>

Yolanda Inmaculada Alacid Mart\u00ednez<\/strong><\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/noelia-sanchez.jpg\" url_new_window=\"on\" align=\"center\" force_fullwidth=\"on\" _builder_version=\"4.2.2\" module_alignment=\"center\" custom_margin=\"||14px|||\" custom_padding=\"|50px||50px|false|false\"][\/et_pb_image][et_pb_text _builder_version=\"4.2.2\" text_orientation=\"center\" link_option_url_new_window=\"on\"]<\/p>

Roc\u00edo D\u00edaz Puertas<\/b><\/span><\/p>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"3px||11px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" header_2_font_size_tablet=\"\" header_2_font_size_phone=\"40px\" header_2_font_size_last_edited=\"on|phone\"]<\/p>

T\u00e9cnicos\u00a0<\/strong><\/span><\/h2>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_3,1_3,1_3\" use_custom_gutter=\"on\" _builder_version=\"4.2.2\" custom_margin=\"0px|auto|67px|auto|false|false\" custom_padding=\"31px||3px||false|false\"][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/05\/Francisco-Alvarez.jpg\" url_new_window=\"on\" align=\"center\" force_fullwidth=\"on\" _builder_version=\"4.2.2\" module_alignment=\"center\" custom_margin=\"||14px|||\" custom_padding=\"|50px||50px|false|false\"][\/et_pb_image][et_pb_text _builder_version=\"4.2.2\" text_orientation=\"center\" link_option_url_new_window=\"on\"]<\/p>

Elisa P\u00e9rez Garc\u00eda<\/strong><\/span><\/p>

[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.2.2\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_padding=\"80px||87px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" header_2_font_size_tablet=\"\" header_2_font_size_phone=\"40px\" header_2_font_size_last_edited=\"on|phone\"]<\/p>

Publicaciones <\/span>representativas<\/span><\/strong><\/h2>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_margin=\"-60px||-60px||true|false\" custom_padding=\"1px||0px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_accordion open_toggle_text_color=\"#000000\" open_toggle_background_color=\"#ffffff\" closed_toggle_text_color=\"#000000\" closed_toggle_background_color=\"#ffffff\" icon_color=\"#ab1a2d\" use_icon_font_size=\"on\" icon_font_size=\"32px\" _builder_version=\"4.2.2\" toggle_text_color=\"#000000\" toggle_font=\"|700|||||||\" toggle_font_size=\"20px\" closed_toggle_font=\"||||||||\" body_text_color=\"#ffffff\" body_font_size=\"18px\" body_line_height=\"1.8em\" background_enable_color=\"off\" module_alignment=\"center\" height_tablet=\"\" height_phone=\"\" height_last_edited=\"on|desktop\" custom_padding=\"12px||||false|false\" border_width_all=\"3px\" border_color_all=\"#ab1a2d\" box_shadow_style=\"preset3\"][et_pb_accordion_item open=\"on\" _builder_version=\"4.2.2\" custom_css_main_element=\"display:none;\"][\/et_pb_accordion_item][et_pb_accordion_item title=\"Formation of multicolor nanogels based on cationic polyfluorenes and poly(methyl vinyl ether-alt-maleic monoethyl ester): Potential use as pH-responsive fluorescent drug carriers\" closed_toggle_text_color=\"#000000\" icon_color=\"#ab1a2d\" use_icon_font_size=\"on\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_color=\"#ffffff\" background_enable_color=\"on\" border_width_top=\"3px\" toggle_level=\"h5\" toggle_font=\"|600|||||||\" toggle_font_size=\"20px\" open=\"off\"]<\/p>

Rubio-Camacho M, Mart\u00ednez-Tom\u00e9 MJ, Mira A, Mallavia R, Mateo CR. Formation of multicolor nanogels based on cationic polyfluorenes and poly(methyl vinyl ether-alt-maleic monoethyl ester): Potential use as pH-responsive fluorescent drug carriers.<\/span> Int. J. Mol. Sci. 2021, 22:9607. doi.org\/10.3390\/ijms22179607.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Reusable fluorescent nanobiosensor integrated in a multiwell plate for screening and quantification of antidiabetic drugs\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Alacid Y, Mart\u00ednez-Tom\u00e9 MJ, Mateo CR. Reusable fluorescent nanobiosensor integrated in a multiwell plate for screening and quantification of antidiabetic drugs.<\/span> ACS Appl. Mater. Interfaces 2021, 13:25624\u221225634. doi.org\/10.1021\/acsami.1c02505.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Modulation of the Tissue Expression Pattern of Zebrafish CRP-Like Molecules Suggests a Relevant Antiviral Role in Fish Skin\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" custom_margin=\"-33px||-3px||false|false\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Bello-Perez M, Adamek M, Coll J, Figueras A, Novoa B, Falco A. Modulation of the Tissue Expression Pattern of Zebrafish CRP-Like Molecules Suggests a Relevant Antiviral Role in Fish Skin. Biology (Basel). 2021 Jan 22;10(2):78. doi: 10.3390\/biology10020078.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"The interaction of temozolomide with blood components suggests the potential use of human serum albumin as a biomimetic carrier for the drug\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" custom_margin=\"||-3px||false|false\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Rubio-Camacho M, Encinar JA, Mart\u00ednez-Tom\u00e9 MJ, Esquembre R, Mateo CR. The interaction of temozolomide with blood components suggests the potential use of human serum albumin as a biomimetic carrier for the drug.<\/span> Biomolecules. 2020, 10:1015. doi:10.3390\/biom10071015.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Electrospun Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Falc\u00f3, A. and Mallavia, R. Electrospun Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering. <\/span>Nanomaterials, <\/span><\/i>2020, <\/span>10(9): 1714. <\/span>doi.org\/10.3390\/nano10091714<\/span><\/a>.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Physico-Chemically Distinct Nanomaterials Synthesized from Derivatives of a Poly(Anhydride)\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" custom_margin=\"-33px||-3px||false|false\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Mira, A., Sainz-Urruela, C.; Codina, H. Jenkins, S.I.; Rodriguez-Diaz, J.C.; Mallavia, R. and Falc\u00f3, A. Physico-Chemically Distinct Nanomaterials Synthesized from Derivatives of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics, <\/span>Nanomaterials,<\/span><\/i> 2020,<\/span> 10<\/span><\/i>(3): 486<\/span>. <\/span>doi.org\/10.3390\/nano10030486<\/span><\/a><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Fluorene-Based Donor-Acceptor Copolymers Containing Functionalized Benzotriazole Units: Tunable Emission and their Electrical Properties\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Torres-Moya, I; V\u00e1zquez-Guill\u00f3, R. Fern\u00e1ndez-Palacios, S. Carrillo, J.R., D\u00edaz-Ortiz, A. Navarrete, J.T.L.; Ortiz, R. P.; Delgado, M.C. R.; Mallavia, R. and Prieto, P. <\/span>2020<\/b>. Fluorene-Based Donor-Acceptor Copolymers Containing Functionalized Benzotriazole Units: Tunable Emission and their Electrical Properties, <\/span>Polymers<\/span><\/i>, 2020,<\/span> 2<\/span><\/i>(2): 256. <\/span>doi.org\/10.3390\/polym12020256<\/span><\/a>.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Canonical and Noncanonical Autophagy as Potential Targets for COVID-19\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" custom_margin=\"-33px||-3px||false|false\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Bello-Perez M, Sola I, Novoa B, Klionsky DJ, Falco A. Canonical and Noncanonical Autophagy as Potential Targets for COVID-19, Cells. 2020, 5;9(7):1619. doi: 10.3390\/cells9071619.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Bello-Perez M, Pereiro P, Coll J, Novoa B, Perez L, Falco A. Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol. Sci Rep. 2020, 17;10(1):566. doi: 10.1038\/s41598-020-57501-0.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Polyfluorene-based multicolor fluorescent nanoparticles activated by temperature for bioimaging and drug delivery\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" custom_margin=\"-33px||-3px||false|false\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Rubio-Camacho M, Alacid Y, Mallavia R, Mart\u00ednez-Tom\u00e9 MJ, Mateo CR. Polyfluorene-based multicolor fluorescent nanoparticles activated by temperature for bioimaging and drug delivery.<\/span> Nanomaterials. 2019, 9:1485.<\/span> doi:10.3390\/nano9101485.<\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion\" closed_toggle_text_color=\"#000000\" _builder_version=\"4.2.2\" body_text_color=\"#000000\" background_enable_color=\"off\" transform_translate=\"0px|-33px\" toggle_font=\"|600|||||||\" open=\"off\"]<\/p>

Falco A, Medina-Gali RM, Poveda JA, Bello-Perez M, Novoa B, Encinar JA. Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion. Mar Drugs. 2019, 1;17(2):87. doi: 10.3390\/md17020087. <\/span><\/p>

[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_enable_color=\"off\" custom_padding=\"80px||87px|||\" disabled=\"on\"][et_pb_row disabled_on=\"off|off|off\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" custom_margin=\"-60px|411px|-60px|auto|true|false\" custom_padding=\"1px||0px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_accordion open_toggle_text_color=\"#ffffff\" open_toggle_background_color=\"#ffffff\" closed_toggle_text_color=\"#ffffff\" closed_toggle_background_color=\"#ab1a2d\" icon_color=\"#ffffff\" use_icon_font_size=\"on\" icon_font_size=\"32px\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" toggle_font=\"|700|||||||\" toggle_font_size=\"20px\" closed_toggle_font=\"||||||||\" body_text_color=\"#ffffff\" body_font_size=\"18px\" body_line_height=\"1.8em\" background_enable_color=\"off\" module_alignment=\"center\" height_tablet=\"\" height_phone=\"\" height_last_edited=\"on|desktop\" border_color_all=\"rgba(0,0,0,0)\" border_color_bottom=\"#ffffff\" disabled=\"on\"][et_pb_accordion_item open=\"on\" _builder_version=\"4.2.2\" custom_css_main_element=\"display:none;\"][\/et_pb_accordion_item][et_pb_accordion_item title=\" %22A Nudibranch Marine Extract Selectively Chemosensitizes Colorectal Cancer Cells by Inducing ROS-Mediated Endoplasmic Reticulum Stress.%22\" _builder_version=\"4.2.2\" background_color=\"rgba(0,0,0,0)\" background_enable_color=\"on\" background_enable_image=\"off\" link_option_url_new_window=\"on\" open=\"off\"]<\/p>

Ruiz-Torres, V., N. Forsythe, et al. (2021). \"A Nudibranch Marine Extract Selectively Chemosensitizes Colorectal Cancer Cells by Inducing ROS-Mediated Endoplasmic Reticulum Stress.\" Frontiers in Pharmacology 12(261). <\/span>https:\/\/doi.org\/10.3389\/fphar.2021.625946<\/span><\/a><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\" %22The antimicrobial capacity of Cistus salviifolius and Punica granatum plant extracts against clinical pathogens is related to their polyphenolic composition.%22\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" background_enable_color=\"on\" open=\"off\"]<\/p>

\u00c1lvarez-Mart\u00ednez, F. J., J. C. Rodr\u00edguez, et al. (2021). \"The antimicrobial capacity of <\/span>Cistus salviifolius<\/span><\/i> and <\/span>Punica granatum <\/span><\/i>plant extracts against clinical pathogens is related to their polyphenolic composition.\" Scientific Reports 11(1): 588. <\/span>https:\/\/doi.org\/10.1038\/s41598-020-80003-y<\/span><\/a><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"%22Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action.%22\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" background_enable_color=\"on\" open=\"off\"]<\/p>

\u00c1lvarez-Mart\u00ednez, F. J., E. Barraj\u00f3n-Catal\u00e1n, et al. (2021). \"Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action.\" Phytomedicine 90: 153626. <\/span>https:\/\/doi.org\/10.1016\/j.phymed.2021.153626<\/span><\/a><\/p>

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E. Barraj\u00f3n-Catal\u00e1n; F.J. \u00c1lvarez-Mart\u00ednez; F. Borr\u00e1s; D.P\u00e9rez; N. Herrero; J.J. Ruiz; V. Micol. Metabolomic analysis of the effects of a commercial complex biostimulant on pepper crops. Food Chemistry. 310 - 125818, pp.1 - 9. <\/span>https:\/\/doi.org\/10.1016\/j.foodchem.2019.125818<\/span><\/a><\/p>

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Agull\u00f3-Chazarra, L., I. Borr\u00e1s-Linares, et al. (2020). \"Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties.\" Antioxidants 9(5): 418. <\/span>https:\/\/doi.org\/10.3390\/antiox9050418<\/span><\/a><\/p>

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S\u00e1nchez-Marzo, N., A. P\u00e9rez-S\u00e1nchez, et al. (2019). \"Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers.\" International Journal of Molecular Sciences 20(9): 2148. <\/span>https:\/\/doi.org\/10.3390\/ijms20092148<\/span><\/a><\/p>

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Boix-Castej\u00f3n, M., M. Herranz-L\u00f3pez, et al. (2021). \"Effect of Metabolaid<\/span>\u00ae<\/span> on pre- and stage 1 hypertensive patients: A randomized controlled trial.\" Journal of Functional Foods 84: 104583. <\/span>https:\/\/doi.org\/10.1016\/j.jff.2021.104583<\/span><\/a><\/p>

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Herranz-L\u00f3pez, M., M. Olivares-Vicente, et al. (2020). \"Quercetin metabolites from <\/span>Hibiscus sabdariffa<\/span><\/i> contribute to alleviate glucolipotoxicity-induced metabolic stress in vitro.\" Food and Chemical Toxicology 144: 111606. <\/span>https:\/\/doi.org\/10.1016\/j.fct.2020.111606<\/span><\/a><\/p>

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S\u00e1nchez-Marzo, N., A. P\u00e9rez-S\u00e1nchez, et al. (2020). \"Rosemary Diterpenes and Flavanone Aglycones Provide Improved Genoprotection against UV-Induced DNA Damage in a Human Skin Cell Model.\" Antioxidants 9(3): 255. <\/span>https:\/\/doi.org\/10.3390\/antiox9030255<\/span><\/a><\/p>

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Herranz-L\u00f3pez, M., M. Olivares-Vicente, et al. (2019). \"Differential effects of a combination of Hibiscus sabdariffa and <\/span>Lippia citriodora<\/span><\/i> polyphenols in overweight\/obese subjects: A randomized controlled trial.\" Scientific Reports 9(1): 2999. <\/span>https:\/\/doi.org\/10.1038\/s41598-019-39159-5<\/span><\/a><\/p>

[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" custom_padding=\"80px||3px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" custom_padding=\"11px||4px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\" header_font_size=\"55px\" header_2_font=\"|||||on|||\" header_2_text_color=\"#2f0ccc\" header_2_font_size=\"48px\" custom_padding=\"||10px|||\"]<\/p>

Patentes<\/b><\/span><\/h2>

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" custom_padding=\"80px||87px|||\" disabled=\"on\"][et_pb_row _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" custom_margin=\"-60px||-60px||true|false\" custom_padding=\"1px||0px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_accordion open_toggle_text_color=\"#ffffff\" open_toggle_background_color=\"#f05227\" closed_toggle_text_color=\"#ffffff\" closed_toggle_background_color=\"#f05227\" icon_color=\"#ffffff\" use_icon_font_size=\"on\" icon_font_size=\"32px\" _builder_version=\"4.2.2\" toggle_font=\"|700|||||||\" toggle_font_size=\"20px\" closed_toggle_font=\"||||||||\" body_text_color=\"#ffffff\" body_font_size=\"18px\" body_line_height=\"1.8em\" background_color=\"#ab1a2d\" module_alignment=\"center\" height_tablet=\"\" height_phone=\"\" height_last_edited=\"on|desktop\" border_color_all=\"rgba(0,0,0,0)\" border_color_bottom=\"#ffffff\"][et_pb_accordion_item open=\"on\" _builder_version=\"4.2.2\" custom_css_main_element=\"display:none;\"][\/et_pb_accordion_item][et_pb_accordion_item title=\"Production of new polymer liquid crystals capable of having an interaction with liposomes\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" background_enable_color=\"on\" open=\"off\"]<\/p>

Inventors: M.M. P\u00e9rez-M\u00e9ndez and C.R. Mateo.<\/span><\/p>

Propietor: CSIC<\/span><\/p>

Number: WO\/1998\/031347.<\/span><\/p>

Date of publication: 23 de julio 1998. <\/span><\/p>

[\/et_pb_accordion_item][et_pb_accordion_item title=\"P\u00e9ptido de miticina y su uso en regeneraci\u00f3n celular\" _builder_version=\"4.2.2\" background_color=\"#ab1a2d\" background_enable_color=\"on\" open=\"off\"]<\/p>

Inventors: Antonio Figueras Huerta, Maria Gasset Vega, Beatriz Novoa Garc\u00eda, Magal\u00ed Rey Campos, Ricardo Mallavia Marin, Regla Maria Medina Gali, Alicia Mart\u00ednez L\u00f3pez.<\/span> N\u00ba. de solicitud: P201831154.\u00a0<\/span><\/p>

Fecha de prioridad: 28 noviembre 2018.<\/span><\/p>

Pa\u00eds de prioridad: ES (ES2763349A1).<\/span><\/p>

Entidades titulares: Consejo Superior de Investigaciones Cient\u00edficas y Universidad Miguel Hern\u00e1ndez.\u00a0<\/span><\/p>

[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.2.2\"][et_pb_row _builder_version=\"4.2.2\"][et_pb_column type=\"4_4\" _builder_version=\"4.2.2\"][et_pb_text _builder_version=\"4.2.2\"][\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2044"}],"collection":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/users\/23459"}],"replies":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/comments?post=2044"}],"version-history":[{"count":0,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2044\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media?parent=2044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}