{"id":2475,"date":"2023-07-28T07:49:36","date_gmt":"2023-07-28T07:49:36","guid":{"rendered":"https:\/\/newidibe.zeus.umh.es\/?page_id=2475"},"modified":"2024-01-30T16:24:20","modified_gmt":"2024-01-30T16:24:20","slug":"dr-jose-m-gonzalez-navajas","status":"publish","type":"page","link":"https:\/\/idibe.umh.es\/en\/dr-jose-m-gonzalez-navajas\/","title":{"rendered":"Dr. Jose M. Gonz\u00e1lez-Navajas"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; custom_padding=&#8221;16px|0px|16px|0px|false|false&#8221; border_width_top=&#8221;3px&#8221; border_color_top=&#8221;#AB1A2D&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;11px|0px|0|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/idibe.umh.es\/files\/2023\/03\/Jose-Manuel-Gonzalez-Navajas.png&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;150px||||false|false&#8221; custom_padding_tablet=&#8221;10px||||false|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;55px&#8221; header_2_font=&#8221;Raleway||||||||&#8221; header_2_text_color=&#8221;#000000&#8243; header_2_font_size=&#8221;45px&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#ffffff&#8221; custom_margin=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 style=\"text-align: center\"><strong>Dr. Jose Manuel Gonz\u00e1lez-Navajas<\/strong><\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_2_font=&#8221;||||||||&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;|||on|||||&#8221; header_4_text_align=&#8221;center&#8221; header_4_text_color=&#8221;#ffffff&#8221; header_4_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;-31px|107px||107px||false&#8221; custom_padding=&#8221;0px||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4><span style=\"color: #333333\">associate Professor, department of pharmacology, Universidad Miguel Hernandez<\/span><\/h4>\n<p>&nbsp;<br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; background_enable_image=&#8221;off&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;36px|0px|35px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x5d;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;20px|20px|1px|20px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Unit<\/strong><br \/> Liver and GI diseases<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x5e;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<strong>Subunit<\/strong><br \/>\nEnvironmental Signaling and Disease<br \/>\n[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe08b;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.17.4&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><strong>Group<\/strong><br \/><span>Liver Cancer Immunology and Immunotherapy<\/span><\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe076;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<span style=\"color: #333333\"><a style=\"color: #333333\" href=\"mailto:jose.gonzalezn@umh.es\"><span style=\"font-weight: 400\">jose.gonzalezn@umh.es<\/span><\/a><\/span>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|3px|false|false&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/orcid.org\/0000-0002-1591-939X\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/idibe.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|3px|false|false&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/www.linkedin.com\/in\/jos%C3%A9-m-gonz%C3%A1lez-navajas-6046b521\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" class=\"wp-image-796 alignnone size-thumbnail\" src=\"http:\/\/idibe.umh.es\/files\/2023\/03\/linkedinlogo-150x150.png\" alt=\"\" width=\"23\" height=\"68\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|20px|3px|false|false&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/scholar.google.com\/citations?user=DN3Wp1YAAAAJ&amp;hl=en&amp;oi=ao\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" class=\"wp-image-775 alignnone size-medium\" src=\"http:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" srcset=\"https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png 300w, https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-480x81.png 480w, https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo.png 762w\" sizes=\"(max-width: 114px) 100vw, 114px\" \/><\/a>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe090;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||||false|false&#8221; custom_padding=&#8221;0px|20px|20px|20px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]+34 96 522 2002<br \/>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#c0172d&#8221; header_4_font_size=&#8221;25px&#8221; header_4_line_height=&#8221;1.4em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>RESEARCH FIELDS<\/h4>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;15px&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_5_font=&#8221;||||||||&#8221; header_6_font=&#8221;||||||||&#8221; custom_margin=&#8221;-31px||0px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Immunobiology of hepatic and digestive diseases.<\/li>\n<li>Study of the role of the Inflammasome complex during chronic liver inflammation and cancer.<\/li>\n<li>Study of the impact of T helper 17 (Th17) cells on the development of liver cancer and the efficacy of immune checkpoint inhibition therapy.<\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_toggle title=&#8221;PROFESSIONAL BACKGROUND&#8221; icon_color=&#8221;#c0172d&#8221; open_icon_color=&#8221;#c0172d&#8221; _builder_version=&#8221;4.16&#8243; title_text_color=&#8221;#c0172d&#8221; title_level=&#8221;h4&#8243; title_font=&#8221;||||||||&#8221; body_font=&#8221;||||||||&#8221; body_text_align=&#8221;justify&#8221; body_text_color=&#8221;#000000&#8243; background_color=&#8221;#ffffff&#8221; custom_padding=&#8221;32px|32px|32px|32px|true|true&#8221; border_radii=&#8221;on|3px|3px|3px|3px&#8221; border_width_all=&#8221;0px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_color=&#8221;rgba(153,153,153,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li><strong>Previous positions:<\/strong><br \/> 1. Senior Researcher, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain, 2020-present.<br \/> 2. Associate Professor, Universidad Miguel Hern\u00e1ndez (UMH), Spain, 2019-present.<br \/> 3. \u2018Miguel Servet\u2019 Researcher of the Spanish National Health System, FISABIO Foundation, Alicante General Hospital, Spain, 2010-2019.<br \/> 4. Assistant Project Scientist, Dept. of Medicine, University of California San Diego (UCSD), USA, 2010-2013.<\/li>\n<li><strong>Postdoctoral positions:<\/strong><br \/> 1. Postdoctoral Employee, Dept. of Medicine, University of California San Diego (UCSD), USA, 2006-2010.<br \/> 2. Postdoctoral Fellowship, Spanish Association for the Study of the Liver (AEEH). Dept. of Medicine, University of California San Diego, USA, 2005-2006.<br \/> 3. Postdoctoral Fellowship, Dept. of Clinical Medicine, Universidad Miguel Hern\u00e1ndez (UMH), Spain, 2004-2005.<\/li>\n<li><strong>PhD<\/strong>\u00a0in Biology. Universidad de Alicante, Spain (2003).<\/li>\n<li><strong>Degree<\/strong>\u00a0in Biology. Universidad de Alicante, Spain (1999).<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;30.375px|0px|0|0px|false|false&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#c0172d&#8221; header_4_font_size=&#8221;26px&#8221; header_4_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;||8px&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>REPRESENTATIVE PUBLICATIONS<\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MART\u00cdNEZ-CARDONA, C. ET AL. (2018)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Internatinal Journal of Cancer, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1002\/ijc.31827\" target=\"_blank\" rel=\"noopener noreferrer\">10.1002\/ijc.31827<\/a><\/p>\n<p><em>AIM2 deficiency reduces the development of hepatocellular carcinoma in mice.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;BERTIN, S. ET AL. (2015)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Mucosal Immunology, DOI:\u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1038\/mi.2014.84\" target=\"_blank\" rel=\"noopener noreferrer\">10.1038\/mi.2014.84<\/a><\/p>\n<p><em>Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;LOZANO-RUIZ, B. ET AL. (2015)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal of Hepatology, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.jhep.2014.08.027\" target=\"_blank\" rel=\"noopener noreferrer\">10.1016\/j.jhep.2014.08.027<\/a><\/p>\n<p><em>Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2012)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Nature Reviews Immunology , DOI:\u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1038\/nri3133\" target=\"_blank\" rel=\"noopener noreferrer\">10.1038\/nri3133<\/a><\/p>\n<p><em>Immunomodulatory functions of type I interferons.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2010)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal of Experimental Medicine, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1084\/jem.20101326\" target=\"_blank\" rel=\"noopener noreferrer\">10.1084\/jem.20101326<\/a><\/p>\n<p><em>Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9\u2013driven antiinflammatory cytokine production.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2010)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal of Clinical Investigation, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1172\/JCI40055\" target=\"_blank\" rel=\"noopener noreferrer\">10.1172\/JCI40055<\/a><\/p>\n<p><em>TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice.<\/em><br \/>\n[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Jose Manuel Gonz\u00e1lez-Navajasassociate Professor, department of pharmacology, Universidad Miguel Hernandez &nbsp; Unit Liver and GI diseasesSubunit Environmental Signaling and Disease GroupLiver Cancer Immunology and Immunotherapyjose.gonzalezn@umh.es+34 96 522 2002 RESEARCH FIELDS Immunobiology of hepatic and digestive diseases. Study of the role of the Inflammasome complex during chronic liver inflammation and cancer. Study of the impact [&hellip;]<\/p>\n","protected":false},"author":3782,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[et_pb_section fb_built=\"1\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_padding=\"16px|0px|16px|0px|false|false\" border_width_top=\"3px\" border_color_top=\"#AB1A2D\"][et_pb_row column_structure=\"1_3,2_3\" _builder_version=\"4.2.2\" custom_padding=\"11px|0px|0|0px|false|false\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/03\/Jose-Manuel-Gonzalez-Navajas.png\" align=\"center\" _builder_version=\"4.2.2\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.2.2\" custom_padding=\"150px||||false|false\" custom_padding_tablet=\"10px||||false|false\" custom_padding_phone=\"\" custom_padding_last_edited=\"on|tablet\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_font_size=\"55px\" header_2_font=\"Raleway||||||||\" header_2_text_color=\"#000000\" header_2_font_size=\"45px\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#ffffff\" custom_margin=\"||||false|false\" hover_enabled=\"0\"]<\/p><h2 style=\"text-align: center;\"><strong><span style=\"color: #333333;\">Dr<\/span>. Jose M. <span style=\"color: #333333;\">Gonz\u00e1lez-Navajas<\/span><\/strong><\/h2><p>[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_2_font=\"||||||||\" header_3_font=\"||||||||\" header_4_font=\"|||on|||||\" header_4_text_align=\"center\" header_4_text_color=\"#ffffff\" header_4_line_height=\"1.4em\" custom_margin=\"-31px|107px||107px||false\" custom_padding=\"0px||\"]<\/p><h4><span style=\"color: #333333;\">associate Professor, department of pharmacology, Universidad Miguel Hernandez<\/span><\/h4><p>\u00a0<\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" background_enable_image=\"off\" parallax=\"on\" custom_padding=\"36px|0px|35px|0px|false|false\"][et_pb_row column_structure=\"1_3,2_3\" _builder_version=\"4.16\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb use_icon=\"on\" font_icon=\"%%60%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"20px|20px|1px|20px|false|true\"]<\/p><p><strong>Unit<\/strong><br \/>Molecular and Cellular Design<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%61%%\" icon_color=\"#c0172d\" icon_placement=\"left\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\" disabled=\"on\"]<\/p><p><strong>Subunit<\/strong><br \/>Environmental Signaling and Disease<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%259%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\"]<\/p><p><strong>Group<\/strong><br \/>Diabetes Research Unit<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%238%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\"]<span style=\"color: #333333;\"><a style=\"color: #333333;\" href=\"mailto:jose.gonzalezn@umh.es\"><span style=\"font-weight: 400;\">jose.gonzalezn@umh.es<\/span><\/a><\/span>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|3px|false|false\"]<a href=\"https:\/\/orcid.org\/0000-0002-1591-939X\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|3px|false|false\"]<a href=\"https:\/\/www.linkedin.com\/in\/jos%C3%A9-m-gonz%C3%A1lez-navajas-6046b521\" target=\"_blank\" rel=\"noopener\"><img class=\"wp-image-796 alignnone size-thumbnail\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/03\/linkedinlogo-150x150.png\" alt=\"\" width=\"23\" height=\"68\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|20px|3px|false|false\"]<\/p><p><a href=\"https:\/\/scholar.google.com\/citations?user=DN3Wp1YAAAAJ&hl=en&oi=ao\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-775 alignnone size-medium\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" \/><\/a><\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%264%%\" icon_color=\"#c0172d\" icon_placement=\"left\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||||false|false\" custom_padding=\"0px|20px|20px|20px|false|true\" disabled=\"on\"]<\/p><p>+34 96 522 2002<\/p><p>[\/et_pb_blurb][et_pb_text disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" background_color=\"#ffffff\" text_orientation=\"center\" custom_margin=\"-25px||||false|false\" custom_padding=\"0px|0px|40px|0px|false|true\" disabled=\"on\"]<\/p><p style=\"text-align: left; padding-left: 30px;\"><a href=\"https:\/\/orcid.org\/0000-0003-1065-5388\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a><\/p><p style=\"padding-left: 30px;\"><a href=\"https:\/\/scholar.google.es\/citations?user=othzU4sAAAAJ&hl=es\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-775 alignnone size-medium\" style=\"float: left;\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" \/><\/a><\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"25px\" header_4_line_height=\"1.4em\"]<\/p><h4>RESEARCH FIELDS<\/h4><p>[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_font=\"||||||||\" text_text_color=\"#000000\" text_font_size=\"15px\" header_font=\"||||||||\" header_2_font=\"||||||||\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_5_font=\"||||||||\" header_6_font=\"||||||||\" custom_margin=\"-31px||0px\"]<\/p><ul><li>Immunobiology of hepatic and digestive diseases.<\/li><li>Study of the role of the Inflammasome complex during chronic liver inflammation and cancer.\u00a0<\/li><li>Study of the impact of T helper 17 (Th17) cells on the development of liver cancer and the efficacy of immune checkpoint inhibition therapy.<\/li><\/ul><p>[\/et_pb_text][et_pb_toggle title=\"PROFESSIONAL BACKGROUND\" icon_color=\"#c0172d\" _builder_version=\"4.2.2\" title_text_color=\"#c0172d\" title_level=\"h4\" title_font=\"||||||||\" body_font=\"||||||||\" background_color=\"#ffffff\" custom_padding=\"32px|32px|32px|32px|true|true\" border_radii=\"on|3px|3px|3px|3px\" border_width_all=\"0px\" box_shadow_style=\"preset1\" box_shadow_color=\"rgba(153,153,153,0.14)\"]<\/p><ul><li><strong>Previous positions:<\/strong><br \/>1. Senior Researcher, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain, 2020-present.<br \/>2. Associate Professor, Universidad Miguel Hern\u00e1ndez (UMH), Spain, 2019-present.<br \/>3. \u2018Miguel Servet\u2019 Researcher of the Spanish National Health System, FISABIO Foundation, Alicante General Hospital, Spain, 2010-2019.<br \/>4. Assistant Project Scientist, Dept. of Medicine, University of California San Diego (UCSD), USA, 2010-2013.<\/li><li><strong>Postdoctoral positions:<\/strong><br \/>1. Postdoctoral Employee, Dept. of Medicine, University of California San Diego (UCSD), USA, 2006-2010.<br \/>2. Postdoctoral Fellowship, Spanish Association for the Study of the Liver (AEEH). Dept. of Medicine, University of California San Diego, USA, 2005-2006.<br \/>3. Postdoctoral Fellowship, Dept. of Clinical Medicine, Universidad Miguel Hern\u00e1ndez (UMH), Spain, 2004-2005.<\/li><li><strong>PhD<\/strong>\u00a0in Biology. Universidad de Alicante, Spain (2003).<\/li><li><strong>Degree<\/strong>\u00a0in Biology. Universidad de Alicante, Spain (1999).<\/li><\/ul><p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_3,2_3\" disabled_on=\"on|on|on\" _builder_version=\"4.16\" disabled=\"on\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" background_color=\"#ffffff\" text_orientation=\"center\" custom_padding=\"10px|0px|0px|0px|false|true\"]<\/p><p><a href=\"https:\/\/orcid.org\/0000-0003-4178-2152\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"106\" height=\"36\" \/><\/a><\/p><p><a href=\"https:\/\/scholar.google.es\/citations?user=othzU4sAAAAJ&hl=es\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-760 alignnone size-full\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/logo_google_scholar.png\" alt=\"\" width=\"106\" height=\"188\" \/><\/a><\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.16\" custom_padding=\"30.375px|0px|0|0px|false|false\" disabled_on=\"on|on|on\" disabled=\"on\"][et_pb_column type=\"4_4\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.16\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" custom_margin=\"||8px\" custom_padding=\"0px|0px|0px|0px|false|true\"]<\/p><h4>REPRESENTATIVE PUBLICATIONS<\/h4><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled_on=\"on|on|on\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MART\u00cdNEZ-CARDONA, C. ET AL. (2018)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Internatinal Journal of Cancer, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1002\/ijc.31827\" target=\"_blank\" rel=\"noopener noreferrer\">10.1002\/ijc.31827<\/a><\/p><p><em>AIM2 deficiency reduces the development of hepatocellular carcinoma in mice.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"BERTIN, S. ET AL. (2015)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Mucosal Immunology, DOI:\u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1038\/mi.2014.84\" target=\"_blank\" rel=\"noopener noreferrer\">10.1038\/mi.2014.84<\/a><\/p><p><em>Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled_on=\"on|on|on\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"LOZANO-RUIZ, B. ET AL. (2015)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal of Hepatology, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.jhep.2014.08.027\" target=\"_blank\" rel=\"noopener noreferrer\">10.1016\/j.jhep.2014.08.027<\/a><\/p><p><em>Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2012)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Nature Reviews Immunology , DOI:\u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1038\/nri3133\" target=\"_blank\" rel=\"noopener noreferrer\">10.1038\/nri3133<\/a><\/p><p><em>Immunomodulatory functions of type I interferons.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled_on=\"on|on|on\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2010)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal of Experimental Medicine, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1084\/jem.20101326\" target=\"_blank\" rel=\"noopener noreferrer\">10.1084\/jem.20101326<\/a><\/p><p><em>Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9\u2013driven antiinflammatory cytokine production.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"GONZ\u00c1LEZ-NAVAJAS, J. M. ET AL. (2010)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal of Clinical Investigation, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1172\/JCI40055\" target=\"_blank\" rel=\"noopener noreferrer\">10.1172\/JCI40055<\/a><\/p><p><em>TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2475"}],"collection":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/users\/3782"}],"replies":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/comments?post=2475"}],"version-history":[{"count":0,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2475\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media?parent=2475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}