{"id":2533,"date":"2023-07-28T08:36:07","date_gmt":"2023-07-28T08:36:07","guid":{"rendered":"https:\/\/newidibe.zeus.umh.es\/?page_id=2533"},"modified":"2024-06-11T10:01:44","modified_gmt":"2024-06-11T10:01:44","slug":"dra-laura-marroqui","status":"publish","type":"page","link":"https:\/\/idibe.umh.es\/en\/dra-laura-marroqui\/","title":{"rendered":"Dra. Laura Marroqui"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; custom_padding=&#8221;16px|0px|16px|0px|false|false&#8221; border_width_top=&#8221;3px&#8221; border_color_top=&#8221;#AB1A2D&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;11px|0px|0|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/idibe.umh.es\/files\/2023\/03\/Laura-Marroqui.png&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;150px||||false|false&#8221; custom_padding_tablet=&#8221;10px||||false|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;55px&#8221; header_2_font=&#8221;Raleway||||||||&#8221; header_2_text_color=&#8221;#000000&#8243; header_2_font_size=&#8221;45px&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#ffffff&#8221; custom_margin=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 style=\"text-align: center\"><strong>Dr. Laura Marroqui<\/strong><\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_text_color=&#8221;#000000&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_2_font=&#8221;||||||||&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;|||on|||||&#8221; header_4_text_align=&#8221;center&#8221; header_4_text_color=&#8221;#ffffff&#8221; header_4_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;-31px|107px||107px||false&#8221; custom_padding=&#8221;0px||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4><span style=\"color: #000000\">Professor of Phisiology, Miguel Hernandez\u00a0University<\/span><\/h4>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; background_enable_image=&#8221;off&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;36px|0px|35px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x5d;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;20px|20px|1px|20px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Unit<\/strong><br \/> <span>Diabetes Research<\/span><\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x5e;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<strong>Subunit<\/strong><br \/>\nEnvironmental Signaling and Disease[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe08b;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Group<\/strong><br \/> <span>Islet Biology Lab<\/span><\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe076;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_text_color=&#8221;#000000&#8243; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|20px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<span style=\"color: #333333\"><a style=\"color: #333333\" href=\"mailto:lmarroqui@umh.es\"><span style=\"font-weight: 400\">lmarroqui@umh.es<\/span><\/a><\/span>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|3px|false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/www.linkedin.com\/in\/laura-marroqu%C3%AD-esclapez-3a26a763\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" class=\"wp-image-796 alignnone size-thumbnail\" src=\"http:\/\/idibe.umh.es\/files\/2023\/03\/linkedinlogo-150x150.png\" alt=\"\" width=\"23\" height=\"68\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|1px|3px|false|false&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/orcid.org\/0000-0003-2931-9317\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/idibe.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||&#8221; custom_padding=&#8221;0px|20px|20px|3px|false|false&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/scholar.google.es\/citations?user=vgvkwWAAAAAJ&amp;amp;hl=es&amp;amp;oi=ao\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" class=\"wp-image-775 alignnone size-medium\" src=\"http:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" srcset=\"https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png 300w, https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo-480x81.png 480w, https:\/\/idibe.umh.es\/files\/2023\/02\/Google_Scholar_logo.png 762w\" sizes=\"(max-width: 114px) 100vw, 114px\" \/><\/a>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe090;||divi||400&#8243; icon_color=&#8221;#c0172d&#8221; icon_placement=&#8221;left&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;-14px||||false|false&#8221; custom_padding=&#8221;0px|20px|20px|20px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]+34 96 522 2002[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#c0172d&#8221; header_4_font_size=&#8221;25px&#8221; header_4_line_height=&#8221;1.4em&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>RESEARCH FIELDS<\/h4>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;15px&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;||||||||&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_5_font=&#8221;||||||||&#8221; header_6_font=&#8221;||||||||&#8221; custom_margin=&#8221;-31px||0px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li style=\"text-align: justify\">We are a research team based at the Universidad Miguel Hern\u00e1ndez de Elche, interested in pancreatic islet function and survival in health and diabetes. Our research aims to understand the molecular differences between alpha and beta cells that allow the former to survive during diabetes development. This knowledge might help us to protect beta cells and, therefore, to either prevent or slow diabetes progression in susceptible individuals<\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_toggle title=&#8221;PROFESSIONAL BACKGROUND&#8221; icon_color=&#8221;#c0172d&#8221; open_icon_color=&#8221;#c0172d&#8221; _builder_version=&#8221;4.16&#8243; title_text_color=&#8221;#c0172d&#8221; title_level=&#8221;h4&#8243; title_font=&#8221;||||||||&#8221; body_font=&#8221;||||||||&#8221; body_text_align=&#8221;justify&#8221; body_text_color=&#8221;#000000&#8243; background_color=&#8221;#ffffff&#8221; custom_padding=&#8221;32px|32px|32px|32px|true|true&#8221; border_radii=&#8221;on|3px|3px|3px|3px&#8221; border_width_all=&#8221;0px&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_color=&#8221;rgba(153,153,153,0.14)&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li><strong>Previous positions:<\/strong><br \/> 1. Assistant Professor, Department of Physiology, Miguel Hern\u00e1ndez University of Elche, Spain, 2019-.<\/li>\n<li><strong>Postdoctoral position:<\/strong><br \/> 1. Postdoctoral Juan de la Cierva-incorporaci\u00f3n (IJCI-2015-24482). Institute of Bioengineering, Miguel Hern\u00e1ndez University of Elche, Alicante, Spain, 2017-2019.<br \/> 2. ULB Center for Diabetes Research, Medical Faculty, Universit\u00e9 libre de Bruxelles, Brussels, Belgium, 2012-2017.<\/li>\n<li><strong>PhD<\/strong> in Bioengineering, IBMC Program, Institute of Bioengineering, Miguel Hern\u00e1ndez University of Elche, Spain, 2012. (Director: Prof. Ivan Quesada).<br \/> Awarded the Prize to the Best Thesis, Miguel Hern\u00e1ndez University of Elche, 2013.<\/li>\n<li><strong>Degree<\/strong> in Biochemistry, Miguel Hern\u00e1ndez University of Elche, Spain, 2006.<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;30.375px|0px|0|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;||||||||&#8221; header_text_color=&#8221;#c0172d&#8221; header_3_font=&#8221;||||||||&#8221; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#c0172d&#8221; header_4_font_size=&#8221;26px&#8221; header_4_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;||8px&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>REPRESENTATIVE PUBLICATIONS<\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARTINEZ-PINNA J., ET AL. (2019)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs00125-019-4925-y\" target=\"_blank\" rel=\"noopener noreferrer\">10.1007\/s00125-019-4925-y<\/a><\/p>\n<p><em>Oestrogen receptor \u03b2 mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells.<\/em>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARROQUI L., ET AL. (2018)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:\u00a0<a href=\"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/239\/2\/JOE-18-0362.xml\" target=\"_blank\" rel=\"noopener noreferrer\">10.1530\/JOE-18-0362<\/a><\/p>\n<p><em>Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes.<\/em>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARROQUI L., ET AL. (2017)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs00125-016-4201-3\" target=\"_blank\" rel=\"noopener noreferrer\">10.1007\/s00125-016-4201-3<\/a><\/p>\n<p>Interferon-\u03b1 mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes.[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARROQUI L., ET AL. (2015)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.1em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:<a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/64\/11\/3808.long\" target=\"_blank\" rel=\"noopener noreferrer\">10.2337\/db15-0362<\/a><\/p>\n<p><em>TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic \u03b2-Cells.<\/em>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;15px|0px|15px|0px|true|false&#8221; custom_width_px=&#8221;1669px&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARROQUI L., ET AL. (2015)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352396415000791?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">10.1016\/j.ebiom.2015.03.012<\/a><\/p>\n<p><em>Pancreatic \u03b1 Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes.<\/em>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;hover_blurb&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255,255,255,0.5)&#8221; custom_padding=&#8221;|||&#8221; custom_css_main_element=&#8221;box-shadow: 0 20px 80px rgba(50,50,93,.09);&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;MARROQUI L., ET AL. (2015)&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Josefin Sans|||on|||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#c0172d&#8221; header_line_height=&#8221;1.2em&#8221; body_font=&#8221;||||||||&#8221; body_line_height=&#8221;1.3em&#8221; custom_padding=&#8221;25px|25px|25px|25px|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]Journal Title, DOI:\u00a0<a href=\"https:\/\/elifesciences.org\/articles\/06990\" target=\"_blank\" rel=\"noopener noreferrer\">10.7554\/eLife.06990<\/a><\/p>\n<p><em>Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic \u03b1 and \u03b2 cells.<\/em>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Laura MarroquiProfessor of Phisiology, Miguel Hernandez\u00a0University &nbsp;Unit Diabetes ResearchSubunit Environmental Signaling and DiseaseGroup Islet Biology Lablmarroqui@umh.es+34 96 522 2002RESEARCH FIELDS We are a research team based at the Universidad Miguel Hern\u00e1ndez de Elche, interested in pancreatic islet function and survival in health and diabetes. Our research aims to understand the molecular differences between alpha [&hellip;]<\/p>\n","protected":false},"author":3782,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[et_pb_section fb_built=\"1\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" custom_padding=\"16px|0px|16px|0px|false|false\" border_width_top=\"3px\" border_color_top=\"#AB1A2D\"][et_pb_row column_structure=\"1_3,2_3\" _builder_version=\"4.2.2\" custom_padding=\"11px|0px|0|0px|false|false\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/03\/Laura-Marroqui.png\" align=\"center\" _builder_version=\"4.2.2\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.2.2\" custom_padding=\"150px||||false|false\" custom_padding_tablet=\"10px||||false|false\" custom_padding_phone=\"\" custom_padding_last_edited=\"on|tablet\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_font_size=\"55px\" header_2_font=\"Raleway||||||||\" header_2_text_color=\"#000000\" header_2_font_size=\"45px\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#ffffff\" custom_margin=\"||||false|false\" hover_enabled=\"0\"]<\/p><h2 style=\"text-align: center;\"><strong><span style=\"color: #333333;\">Dra<\/span>. Laura<span style=\"color: #333333;\">\u00a0Marroqui<\/span><\/strong><\/h2><p>[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_2_font=\"||||||||\" header_3_font=\"||||||||\" header_4_font=\"|||on|||||\" header_4_text_align=\"center\" header_4_text_color=\"#ffffff\" header_4_line_height=\"1.4em\" custom_margin=\"-31px|107px||107px||false\" custom_padding=\"0px||\"]<\/p><h4><span style=\"color: #333333;\">Professor, Universidad Miguel Hernandez<\/span><\/h4><p>\u00a0<\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"section\" _builder_version=\"4.2.2\" background_color=\"#ffffff\" background_enable_image=\"off\" parallax=\"on\" custom_padding=\"36px|0px|35px|0px|false|false\"][et_pb_row column_structure=\"1_3,2_3\" _builder_version=\"4.16\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb use_icon=\"on\" font_icon=\"%%60%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"20px|20px|1px|20px|false|true\"]<\/p><p><strong>Unit<\/strong><br \/>Molecular and Cellular Design<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%61%%\" icon_color=\"#c0172d\" icon_placement=\"left\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\" disabled=\"on\"]<\/p><p><strong>Subunit<\/strong><br \/>Environmental Signaling and Disease<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%259%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\"]<\/p><p><strong>Group<\/strong><br \/>Diabetes Research Unit<\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%238%%\" icon_color=\"#c0172d\" icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|20px|false|true\"]<span style=\"color: #333333;\"><a style=\"color: #333333;\" href=\"mailto:lmarroqui@umh.es\"><span style=\"font-weight: 400;\">lmarroqui@umh.es<\/span><\/a><\/span>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|3px|false|false\" locked=\"off\"]<a href=\"https:\/\/www.linkedin.com\/in\/laura-marroqu%C3%AD-esclapez-3a26a763\" target=\"_blank\" rel=\"noopener\"><img class=\"wp-image-796 alignnone size-thumbnail\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/03\/linkedinlogo-150x150.png\" alt=\"\" width=\"23\" height=\"68\" \/><\/a>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|1px|3px|false|false\"]<\/p><p><a href=\"https:\/\/orcid.org\/0000-0003-2931-9317\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a><\/p><p>[\/et_pb_blurb][et_pb_blurb icon_placement=\"left\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||\" custom_padding=\"0px|20px|20px|3px|false|false\"]<\/p><p><a href=\"https:\/\/scholar.google.es\/citations?user=vgvkwWAAAAAJ&amp;hl=es&amp;oi=ao\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-775 alignnone size-medium\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" \/><\/a><\/p><p>[\/et_pb_blurb][et_pb_blurb use_icon=\"on\" font_icon=\"%%264%%\" icon_color=\"#c0172d\" icon_placement=\"left\" disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_margin=\"-14px||||false|false\" custom_padding=\"0px|20px|20px|20px|false|true\" disabled=\"on\"]<\/p><p>+34 96 522 2002<\/p><p>[\/et_pb_blurb][et_pb_text disabled_on=\"on|on|on\" _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" background_color=\"#ffffff\" text_orientation=\"center\" custom_margin=\"-25px||||false|false\" custom_padding=\"0px|0px|40px|0px|false|true\" disabled=\"on\"]<\/p><p style=\"text-align: left; padding-left: 30px;\"><a href=\"https:\/\/orcid.org\/0000-0003-1065-5388\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"68\" height=\"23\" \/><\/a><\/p><p style=\"padding-left: 30px;\"><a href=\"https:\/\/scholar.google.es\/citations?user=othzU4sAAAAJ&hl=es\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-775 alignnone size-medium\" style=\"float: left;\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/Google_Scholar_logo-300x50.png\" alt=\"\" width=\"114\" height=\"19\" \/><\/a><\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"25px\" header_4_line_height=\"1.4em\"]<\/p><h4>RESEARCH FIELDS<\/h4><p>[\/et_pb_text][et_pb_text _builder_version=\"4.2.2\" text_font=\"||||||||\" text_text_color=\"#000000\" text_font_size=\"15px\" header_font=\"||||||||\" header_2_font=\"||||||||\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_5_font=\"||||||||\" header_6_font=\"||||||||\" custom_margin=\"-31px||0px\"]<\/p><ul><li>We are a research team based at the Universidad Miguel Hern\u00e1ndez de Elche, interested in pancreatic islet function and survival in health and diabetes. Our research aims to understand the molecular differences between alpha and beta cells that allow the former to survive during diabetes development. This knowledge might help us to protect beta cells and, therefore, to either prevent or slow diabetes progression in susceptible individuals<\/li><\/ul><p>[\/et_pb_text][et_pb_toggle title=\"PROFESSIONAL BACKGROUND\" icon_color=\"#c0172d\" _builder_version=\"4.2.2\" title_text_color=\"#c0172d\" title_level=\"h4\" title_font=\"||||||||\" body_font=\"||||||||\" background_color=\"#ffffff\" custom_padding=\"32px|32px|32px|32px|true|true\" border_radii=\"on|3px|3px|3px|3px\" border_width_all=\"0px\" box_shadow_style=\"preset1\" box_shadow_color=\"rgba(153,153,153,0.14)\"]<\/p><ul><li><strong>Previous positions:\u00a0<\/strong><\/li><\/ul><p>1. Assistant Professor, Department of Physiology, Miguel Hern\u00e1ndez University of Elche, Spain, 2019-.<\/p><ul><li><strong>Postdoctoral position:<\/strong><\/li><\/ul><p>1. Postdoctoral Juan de la Cierva-incorporaci\u00f3n (IJCI-2015-24482). Institute of Bioengineering, Miguel Hern\u00e1ndez University of Elche, Alicante, Spain, 2017-2019.<\/p><p>2. ULB Center for Diabetes Research, Medical Faculty, Universit\u00e9 libre de Bruxelles, Brussels, Belgium, 2012-2017.<\/p><p>\u00a0<\/p><ul><li><strong>PhD in<\/strong>\u00a0Bioengineering, IBMC Program, Institute of Bioengineering, Miguel Hern\u00e1ndez University of Elche, Spain, 2012. (Director: Prof. Ivan Quesada).<\/li><\/ul><p>Awarded the Prize to the Best Thesis, Miguel Hern\u00e1ndez University of Elche, 2013.<\/p><p>\u00a0<\/p><ul><li><strong>Degree in<\/strong>\u00a0Biochemistry, Miguel Hern\u00e1ndez University of Elche, Spain, 2006.<\/li><\/ul><p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_3,2_3\" disabled_on=\"on|on|on\" _builder_version=\"4.16\" disabled=\"on\"][et_pb_column type=\"1_3\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.2.2\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" background_color=\"#ffffff\" text_orientation=\"center\" custom_padding=\"10px|0px|0px|0px|false|true\"]<\/p><p><a href=\"https:\/\/orcid.org\/0000-0003-4178-2152\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-3808 alignnone size-large\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2022\/09\/ORCID_logo.svg_-1024x348-1.png\" alt=\"\" width=\"106\" height=\"36\" \/><\/a><\/p><p><a href=\"https:\/\/scholar.google.es\/citations?user=othzU4sAAAAJ&hl=es\" target=\"_blank\" rel=\"noopener noreferrer\"><img class=\"wp-image-760 alignnone size-full\" src=\"http:\/\/newidibe.zeus.umh.es\/files\/2023\/02\/logo_google_scholar.png\" alt=\"\" width=\"106\" height=\"188\" \/><\/a><\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_3\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.16\" custom_padding=\"30.375px|0px|0|0px|false|false\"][et_pb_column type=\"4_4\" _builder_version=\"4.16\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text disabled_on=\"on|on|on\" _builder_version=\"4.16\" header_font=\"||||||||\" header_text_color=\"#c0172d\" header_3_font=\"||||||||\" header_4_font=\"||||||||\" header_4_text_color=\"#c0172d\" header_4_font_size=\"26px\" header_4_line_height=\"1.4em\" custom_margin=\"||8px\" custom_padding=\"0px|0px|0px|0px|false|true\" disabled=\"on\"]<\/p><h4>REPRESENTATIVE PUBLICATIONS<\/h4><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" disabled_on=\"on|on|on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARTINEZ-PINNA J., ET AL. (2019)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs00125-019-4925-y\" target=\"_blank\" rel=\"noopener noreferrer\">10.1007\/s00125-019-4925-y<\/a><\/p><p><em>Oestrogen receptor \u03b2 mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARROQUI L., ET AL. (2018)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:\u00a0<a href=\"https:\/\/joe.bioscientifica.com\/view\/journals\/joe\/239\/2\/JOE-18-0362.xml\" target=\"_blank\" rel=\"noopener noreferrer\">10.1530\/JOE-18-0362<\/a><\/p><p><em>Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" disabled_on=\"on|on|on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARROQUI L., ET AL. (2017)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs00125-016-4201-3\" target=\"_blank\" rel=\"noopener noreferrer\">10.1007\/s00125-016-4201-3<\/a><\/p><p>Interferon-\u03b1 mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes.<\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARROQUI L., ET AL. (2015)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.1em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:<a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/64\/11\/3808.long\" target=\"_blank\" rel=\"noopener noreferrer\">10.2337\/db15-0362<\/a><\/p><p><em>TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic \u03b2-Cells.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" disabled_on=\"on|on|on\" _builder_version=\"4.16\" custom_padding=\"15px|0px|15px|0px|true|false\" custom_width_px=\"1669px\" disabled=\"on\"][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARROQUI L., ET AL. (2015)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352396415000791?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">10.1016\/j.ebiom.2015.03.012<\/a><\/p><p><em>Pancreatic \u03b1 Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_2\" module_class=\"hover_blurb\" _builder_version=\"4.16\" background_color=\"rgba(255,255,255,0.5)\" custom_padding=\"|||\" custom_css_main_element=\"box-shadow: 0 20px 80px rgba(50,50,93,.09);\" custom_padding__hover=\"|||\"][et_pb_blurb title=\"MARROQUI L., ET AL. (2015)\" _builder_version=\"4.2.2\" header_font=\"Josefin Sans|||on|||||\" header_text_align=\"left\" header_text_color=\"#c0172d\" header_line_height=\"1.2em\" body_font=\"||||||||\" body_line_height=\"1.3em\" custom_padding=\"25px|25px|25px|25px|true\" locked=\"off\"]<\/p><p>Journal Title, DOI:\u00a0<a href=\"https:\/\/elifesciences.org\/articles\/06990\" target=\"_blank\" rel=\"noopener noreferrer\">10.7554\/eLife.06990<\/a><\/p><p><em>Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic \u03b1 and \u03b2 cells.<\/em><\/p><p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2533"}],"collection":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/users\/3782"}],"replies":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/comments?post=2533"}],"version-history":[{"count":0,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/pages\/2533\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media?parent=2533"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}