{"id":23263,"date":"2025-09-12T06:48:32","date_gmt":"2025-09-12T06:48:32","guid":{"rendered":"https:\/\/idibe.umh.es\/?p=23263"},"modified":"2025-09-16T09:57:43","modified_gmt":"2025-09-16T09:57:43","slug":"new-scientific-publication-a-molecular-approach-to-t2d","status":"publish","type":"post","link":"https:\/\/idibe.umh.es\/en\/2025\/09\/12\/new-scientific-publication-a-molecular-approach-to-t2d\/","title":{"rendered":"New scientific publication &#8212; A Molecular Approach to T2D"},"content":{"rendered":"<p>[et_pb_section][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text]<\/p>\n<p style=\"text-align: justify\" data-start=\"60\" data-end=\"99\">New Publication from the IDiBE Team<\/p>\n<p style=\"text-align: justify\" data-start=\"101\" data-end=\"328\">Today we\u2019d like to share the latest work published by researchers from the <strong data-start=\"176\" data-end=\"212\">Diabesity and Islet Research Lab<\/strong> (<a class=\"decorated-link\" href=\"https:\/\/dialab.umh.es\/\" target=\"_new\" rel=\"noopener\" data-start=\"214\" data-end=\"236\">https:\/\/dialab.umh.es\/<\/a>) within the <strong data-start=\"249\" data-end=\"281\">Basic Diabetes Research Unit<\/strong> of our institution (<a class=\"decorated-link\" href=\"https:\/\/diabetes.umh.es\/\" target=\"_new\" rel=\"noopener\" data-start=\"302\" data-end=\"326\">https:\/\/diabetes.umh.es\/<\/a>).<\/p>\n<p style=\"text-align: justify\" data-start=\"330\" data-end=\"651\">The article is led by Dr. <a id=\"ember140\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/ivan-quesada-a4528b47\/\">Ivan Quesada<\/a>\u00a0(IDiBE-UMH) and<strong data-start=\"389\" data-end=\"424\"> Dr. <\/strong><a id=\"ember141\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/everardo-magalh%C3%A3es-carneiro-66aa1a35\/\">Everardo Magalh\u00e3es Carneiro<\/a>\u00a0(Universidade Estadual de Campinas), with contributions from our researchers Paloma Alonso-Magdalena, Sergi Soriano, <a id=\"ember142\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/angel-nadal-55b5681a\/\">Angel Nadal<\/a>, <a id=\"ember143\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/laura-marroqu%C3%AD-esclapez-3a26a763\/\">Laura Marroqu\u00ed Esclapez<\/a>, <a id=\"ember144\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/evabru-tari\/\">Eva Br\u00fa Tar\u00ed<\/a>, <a id=\"ember145\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/taliaboronat\/\">Tal\u00eda Boronat Belda<\/a>, and Manuel Castellano Mu\u00f1oz.<\/p>\n<p style=\"text-align: justify\" data-start=\"653\" data-end=\"1083\">Titled <strong data-start=\"660\" data-end=\"776\">&#8220;Inhibition of glucagon secretion from pancreatic \u03b1-cells by the bile acid TUDCA involves a S1PR2-PI3K pathway,&#8221;<\/strong> the study explores the role of bile acids as metabolic modulators in the context of type 2 diabetes (T2D). It demonstrates that acute administration of the bile acid TUDCA inhibits glucagon secretion in both mouse pancreatic islets and the \u03b1TC1-9 cell line.<br data-start=\"1038\" data-end=\"1041\" \/>More information: <a class=\"decorated-link\" href=\"https:\/\/lnkd.in\/dNVRT25C\" target=\"_new\" rel=\"noopener\" data-start=\"1059\" data-end=\"1083\">https:\/\/lnkd.in\/dNVRT25C<\/a><\/p>\n<p style=\"text-align: justify\" data-start=\"1085\" data-end=\"1217\">These results expand the known therapeutic properties of TUDCA, pointing toward new strategies for glycemic control in diabetes.<\/p>\n<p style=\"text-align: justify\" data-start=\"1219\" data-end=\"1333\">Congratulations to all the authors for this valuable contribution to the search for innovative diabetes therapies!<\/p>\n<p data-start=\"1219\" data-end=\"1333\">\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_section et_pb_section_0 et_section_regular\" >\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div><div class=\"et_pb_module et_pb_text et_pb_text_0  et_pb_text_align_left et_pb_bg_layout_light\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> New Publication from the IDiBE Team Today we\u2019d like to share the latest work published by researchers from the Diabesity and Islet Research Lab (https:\/\/dialab.umh.es\/) within the Basic Diabetes Research Unit of our institution (https:\/\/diabetes.umh.es\/). The article is led by Dr. Ivan Quesada\u00a0(IDiBE-UMH) and Dr. Everardo Magalh\u00e3es Carneiro\u00a0(Universidade Estadual de Campinas), with contributions from [&hellip;]<\/p>\n","protected":false},"author":30306,"featured_media":23290,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p style=\"text-align: justify;\" data-start=\"60\" data-end=\"99\">New Publication from the IDiBE Team<\/p><p style=\"text-align: justify;\" data-start=\"101\" data-end=\"328\">Today we\u2019d like to share the latest work published by researchers from the <strong data-start=\"176\" data-end=\"212\">Diabesity and Islet Research Lab<\/strong> (<a class=\"decorated-link\" href=\"https:\/\/dialab.umh.es\/\" target=\"_new\" rel=\"noopener\" data-start=\"214\" data-end=\"236\">https:\/\/dialab.umh.es\/<\/a>) within the <strong data-start=\"249\" data-end=\"281\">Basic Diabetes Research Unit<\/strong> of our institution (<a class=\"decorated-link\" href=\"https:\/\/diabetes.umh.es\/\" target=\"_new\" rel=\"noopener\" data-start=\"302\" data-end=\"326\">https:\/\/diabetes.umh.es\/<\/a>).<\/p><p style=\"text-align: justify;\" data-start=\"330\" data-end=\"651\">The article is led by Dr. <a id=\"ember140\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/ivan-quesada-a4528b47\/\">Ivan Quesada<\/a>\u00a0(IDiBE-UMH) and<strong data-start=\"389\" data-end=\"424\"> Dr. <\/strong><a id=\"ember141\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/everardo-magalh%C3%A3es-carneiro-66aa1a35\/\">Everardo Magalh\u00e3es Carneiro<\/a>\u00a0(Universidade Estadual de Campinas), with contributions from our researchers Paloma Alonso-Magdalena, Sergi Soriano, <a id=\"ember142\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/angel-nadal-55b5681a\/\">Angel Nadal<\/a>, <a id=\"ember143\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/laura-marroqu%C3%AD-esclapez-3a26a763\/\">Laura Marroqu\u00ed Esclapez<\/a>, <a id=\"ember144\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/evabru-tari\/\">Eva Br\u00fa Tar\u00ed<\/a>, <a id=\"ember145\" class=\"ember-view\" href=\"https:\/\/www.linkedin.com\/in\/taliaboronat\/\">Tal\u00eda Boronat Belda<\/a>, and Manuel Castellano Mu\u00f1oz.<\/p><p style=\"text-align: justify;\" data-start=\"653\" data-end=\"1083\">Titled <strong data-start=\"660\" data-end=\"776\">\"Inhibition of glucagon secretion from pancreatic \u03b1-cells by the bile acid TUDCA involves a S1PR2-PI3K pathway,\"<\/strong> the study explores the role of bile acids as metabolic modulators in the context of type 2 diabetes (T2D). It demonstrates that acute administration of the bile acid TUDCA inhibits glucagon secretion in both mouse pancreatic islets and the \u03b1TC1-9 cell line.<br data-start=\"1038\" data-end=\"1041\" \/>More information: <a class=\"decorated-link\" href=\"https:\/\/lnkd.in\/dNVRT25C\" target=\"_new\" rel=\"noopener\" data-start=\"1059\" data-end=\"1083\">https:\/\/lnkd.in\/dNVRT25C<\/a><\/p><p style=\"text-align: justify;\" data-start=\"1085\" data-end=\"1217\">These results expand the known therapeutic properties of TUDCA, pointing toward new strategies for glycemic control in diabetes.<\/p><p style=\"text-align: justify;\" data-start=\"1219\" data-end=\"1333\">Congratulations to all the authors for this valuable contribution to the search for innovative diabetes therapies!<\/p><p data-start=\"1219\" data-end=\"1333\">\u00a0<\/p>","_et_gb_content_width":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/posts\/23263"}],"collection":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/users\/30306"}],"replies":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/comments?post=23263"}],"version-history":[{"count":0,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/posts\/23263\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media\/23290"}],"wp:attachment":[{"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/media?parent=23263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/categories?post=23263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibe.umh.es\/en\/wp-json\/wp\/v2\/tags?post=23263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}