Dr. Mª del Mar Ortega-Villaizán Romo

Researcher, Universidad Miguel Hernandez


Molecular Diagnostics and Therapies


Antiviral Strategies


Fish erythrocytes in antiviral immunology



+ 34 966 658 431



  • Fish immunology and virology.
  • Evaluation of the crosstalk between red and white blood cells in the scenario of fish viral infections and prophylaxis


  • Previous positions:
    1. Postdoctoral Researcher in Fish Immunology/ Virology. Institute of Molecular and Cell Biology, University Miguel       Hernández, Spain, 2007-2015
  • Postdoctoral positions:
    1. Postdoctoral Researcher in Fish Immunology/Virology. Institute of Molecular and Cell Biology, Universidad Miguel Hernández, Spain, 2007-2015
    2. R&D Manager of the Pathology Laboratory Acuicola Marina S.L., Spain, 2007
    3. Postdoctoral Researcher in Sturgeon Conservation. Genetics CEMAGREF (Bordeaux), France, 2005
  • PhD in Agricultural Sciences, Graduate School of Agricultural Sciences, Division of Environmental Bioremediation, Tohoku University, Japan, 2005. Supervisor: Prof. Nobuhiko Taniguchi
  • Degree in Biology, University of Alicante, 1995



Nombela I. et al. (2019)

Vaccines (Basel), DOI:

Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets.

Puente-Marin S., et al. (2019)

Vaccines (Basel), DOI:

Potencial Role of Rainbow Trout Erytrocytes as Mediators in the Immune Response Induced by a DNA vaccine in Fish.

puente-marin s., et al. (2019)

Front Immunol., DOI:

Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNFα and a G-VHSV Fragment.

CHICO, V., et al. (2019)

Front Immunol., DOI:

IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells.

NOMBELA I., et al. (2019)

Cells, DOI:

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Seoticemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86 and Antigen-presenting Cell Markers.

JUNG MH., et al. (2019)

Front Immunol., DOI:

The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells.

CHICO V., et al. (2018)

IntechOpen, DOI: 10.5772/intechopen.80545

Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens, Immune Response Activation and Immunomodulation.

Puente-Marin S., et al. (2018)

Genes, DOI:

In silico functional networks identified in fish nucleated red blood cells by means of transcriptomic and proteomic profiling

Chico V., et al. (2018)

Cells, DOI: 10.3390/cells7040031

Shape-shifted red blood cells: a novel red blood cell stage? .

nombela i. and ortega-villaizan M. M. (2018)

PLOS Pathogens, DOI: 10.1371/journal.ppat.1006910

Nucleated red blood cells: Immune cell mediators of the antiviral response.