We are back and we hope that you have been able to gather strength during these holidays for an exciting 2025.

We start with our IDiBE – UMH Calendar image for 2025 with the January image entitled ‘The Trojan Horse of Cancer’:

This fluorescence microscopy image shows a battle in the tumour microenvironment (TME) between tumour-infiltrating T lymphocytes (TILS) and cancer cells (DAPI, in blue). Regulatory T cells (Treg), defined by being T helper (Th) or CD4+ lymphocytes (green) and by expression of the FOXP3 marker (magenta), inhibit the anti-tumour response in hepatocellular carcinoma (HCC), creating exhaustion in other Th lymphocytes (green) and aiding tumour evasion.

This year’s calendar has been produced with the images submitted to the IDiBE Scientific Image Competition 2024.

This image was obtained thanks to Joanna Picó Carrasco, from the laboratory of José Manuel González Navajas.