Our researcher Ana María Fernández Escamilla has contributed to a comprehensive review on the West Nile Virus (WNV) — a mosquito-borne orthoflavivirus that represents an increasing global public health threat.
The work, published in Frontiers in Cellular and Infection Microbiology, provides an in-depth and up-to-date overview of the virus, covering everything from its molecular biology to its ecological dynamics and the challenges ahead in its prevention and control.
The review explores key aspects such as:
🔹 The organization and functionality of the viral genome.
🔹 The role of viral proteins in replication and immune evasion.
🔹 The impact of climate change on its geographic expansion.
🔹 The pathogenesis and clinical manifestations in humans and animals.
🔹 Current diagnostic, prevention, and control strategies.
The authors highlight the urgent need to develop human vaccines and effective antiviral therapies, and emphasize the importance of a “One Health” approach — integrating human, animal, and environmental health to tackle emerging infectious diseases.
📖 West Nile virus unmasked: from gene variability to future challenges
🔗 DOI: 10.3389/fcimb.2025.1690827
👏 From IDiBE, we congratulate our researcher for her contribution to this important work, which helps deepen our understanding of emerging viral threats and reinforces our commitment to impactful research in global health.